I0B8M2 · I0B8M2_DROME

Function

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionhistidine decarboxylase activity
Molecular Functionpyridoxal phosphate binding
Biological Processamino acid metabolic process
Biological Processcarboxylic acid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Histidine decarboxylase
  • EC number

Gene names

    • Name
      Hdc
    • Synonyms
      anon-WO0140519.259
      , Dmel\CG3454
      , HDC
      , hdc
      , Hdc-RA
      , JK910
    • ORF names
      CG3454
      , Dmel_CG3454

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    I0B8M2

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue304N6-(pyridoxal phosphate)lysine

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias575-602Polar residues
Region575-662Disordered
Compositional bias617-662Polar residues
Region769-798Disordered
Region813-847Disordered
Compositional bias829-847Polar residues

Sequence similarities

Belongs to the group II decarboxylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    847
  • Mass (Da)
    94,036
  • Last updated
    2012-06-13 v1
  • Checksum
    C04F32F01C176951
MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHRTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHTTLDDIVKDWMEIRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLSNSPLSPKVVNGSFAAIFDADEFLAKTYAGVRIAHQESPSMRRRVRGILMSGKQFSLDSHMDVVVQTTLDAGNGATRTSTTNSYGHTTSAAQANSERQASIQEDNEESPEETELLSLCRTSNVPSPEHAHSLSTPSRSCSSSSHSLIHSLTQSSPRSSPVNQFRPITLCAVPSQSQLSMPLAMPLPNRNVTVSVDSLLNPVTTCNVYHGKRFLEPLENLAQTSASFSSSIFRLPTPIATPTRESPEDPDWPAKTFSQLLLERYSSQSQSLGNNSSTESSSLSGGATPTPTPMSSLDELVTPLLLSFASPSQPMLSAHGIGEGQREQGSDSDATVCSTTSSMESL

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q05733DCHS_DROMEHdc847
A0A0B4KEQ1A0A0B4KEQ1_DROMEHdc619

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias575-602Polar residues
Compositional bias617-662Polar residues
Compositional bias829-847Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BT133422
EMBL· GenBank· DDBJ
AFH58719.1
EMBL· GenBank· DDBJ
mRNA
AE013599
EMBL· GenBank· DDBJ
AGB93388.1
EMBL· GenBank· DDBJ
Genomic DNA
AE013599
EMBL· GenBank· DDBJ
AHN56072.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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