H9YUS5 · H9YUS5_MACMU
- ProteinAprataxin
- GeneAPTX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids356 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- a 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine-DNA + H2O = a 3'-end 2'-deoxyribonucleotide 3'-phosphate-DNA + GMP + 2 H+
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chromatin | |
Cellular Component | nucleolus | |
Cellular Component | nucleoplasm | |
Cellular Component | nucleus | |
Molecular Function | chromatin binding | |
Molecular Function | DNA 5'-adenosine monophosphate hydrolase activity | |
Molecular Function | DNA-3'-diphospho-5'-guanosine diphosphatase | |
Molecular Function | double-stranded RNA binding | |
Molecular Function | metal ion binding | |
Molecular Function | mismatched DNA binding | |
Molecular Function | phosphoglycolate phosphatase activity | |
Molecular Function | phosphoprotein binding | |
Molecular Function | single-strand break-containing DNA binding | |
Molecular Function | single-stranded DNA binding | |
Biological Process | DNA ligation | |
Biological Process | regulation of protein stability | |
Biological Process | single strand break repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAprataxin
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca
Accessions
- Primary accessionH9YUS5
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 122-147 | Basic and acidic residues | ||||
Sequence: GLETHRKRKRSGDSDSIERDAAHEAE | ||||||
Region | 122-173 | Disordered | ||||
Sequence: GLETHRKRKRSGDSDSIERDAAHEAEPGTGLEPGSNHNQCSVPPKKGKDAPI | ||||||
Domain | 182-287 | HIT | ||||
Sequence: SQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTAISSLKAVTREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCL | ||||||
Motif | 272-276 | Histidine triad motif | ||||
Sequence: HVHLH |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length356
- Mass (Da)40,847
- Last updated2012-06-13 v1
- Checksum5C29E1B4D1B9D413
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 122-147 | Basic and acidic residues | ||||
Sequence: GLETHRKRKRSGDSDSIERDAAHEAE |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JU470637 EMBL· GenBank· DDBJ | AFH27441.1 EMBL· GenBank· DDBJ | mRNA | ||
JV047458 EMBL· GenBank· DDBJ | AFI37529.1 EMBL· GenBank· DDBJ | mRNA |