screening of GPR7 gene mutations among lean and obese subjects revealed a Tyr135Phe allelic variant that is fairly common in the study population. This variant is unlikely to cause a functional derangement of the receptor
A single nucleotide polymorphism of NPBWR1 changed the receptor function of this molecule at the cellular level and at the behavioral level could influence personality difference in the context of social interaction.
These results suggest a relationship between the pathogenesis of inflammatory/immune-mediated neuropathies GPR7 receptor expression and pain transmission.
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