H7C078 · H7C078_HUMAN
- ProteinPeroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
- GeneDECR2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H+ + NADPH = (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + NADP+
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2,4-dienoyl-CoA reductase (NADPH) activity | |
Biological Process | fatty acid catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionH7C078
Proteomes
Organism-specific databases
Disease & Variants
Variants
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The viewer provides 245 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Monomer, dimer and oligomer.
Structure
Family & Domains
Sequence similarities
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length94
- Mass (Da)10,012
- Last updated2012-04-18 v1
- Checksum4C7D35DD6306E8C6
Computationally mapped potential isoform sequences
There are 6 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9NUI1 | DECR2_HUMAN | DECR2 | 292 | ||
G3V0I9 | G3V0I9_HUMAN | DECR2 | 81 | ||
A0A0J9YWI0 | A0A0J9YWI0_HUMAN | DECR2 | 238 | ||
A0A0J9YY83 | A0A0J9YY83_HUMAN | DECR2 | 142 | ||
A0A0J9YXZ6 | A0A0J9YXZ6_HUMAN | DECR2 | 82 | ||
Q4VXZ8 | Q4VXZ8_HUMAN | DECR2 | 280 |
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: X |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL023881 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |