H6WE97 · H6WE97_PANTR
- ProteinDeoxynucleoside triphosphate triphosphohydrolase SAMHD1
- GeneSAMHD1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids626 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- a 2'-deoxyribonucleoside 5'-triphosphate + H2O = a 2'-deoxyribonucleoside + triphosphate + H+This reaction proceeds in the forward direction.
- dATP + H2O = 2'-deoxyadenosine + triphosphate + H+This reaction proceeds in the forward direction.
- dCTP + H2O = 2'-deoxycytidine + triphosphate + H+This reaction proceeds in the forward direction.
- dGTP + H2O = 2'-deoxyguanosine + triphosphate + H+This reaction proceeds in the forward direction.
- dTTP + H2O = thymidine + triphosphate + H+This reaction proceeds in the forward direction.
GO annotations
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameDeoxynucleoside triphosphate triphosphohydrolase SAMHD1
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan
Accessions
- Primary accessionH6WE97
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-18 | Basic and acidic residues | |||
Region | 1-35 | Disordered | |||
Domain | 45-110 | SAM | |||
Domain | 164-316 | HD | |||
Sequence similarities
Belongs to the SAMHD1 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length626
- Mass (Da)72,224
- Last updated2012-04-18 v1
- MD5 Checksum27D65B77A13C3A5CE39EE30D5F719BE9
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-18 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AACZ04052781 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
JQ231123 EMBL· GenBank· DDBJ | AFB71157.1 EMBL· GenBank· DDBJ | mRNA | ||
JQ085410 EMBL· GenBank· DDBJ | AFJ79636.1 EMBL· GenBank· DDBJ | mRNA | ||
JQ085411 EMBL· GenBank· DDBJ | AFJ79637.1 EMBL· GenBank· DDBJ | mRNA | ||
JN936887 EMBL· GenBank· DDBJ | AFU88758.1 EMBL· GenBank· DDBJ | mRNA | ||
GABF01006234 EMBL· GenBank· DDBJ | JAA15911.1 EMBL· GenBank· DDBJ | mRNA |