H3D1Z5 · H3D1Z5_TETNG
- ProteinMitogen-activated protein kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids391 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Cofactor
Activity regulation
Activated by threonine and tyrosine phosphorylation.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytoskeleton | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | MAP kinase activity | |
Molecular Function | protein serine kinase activity | |
Biological Process | brain development | |
Biological Process | central nervous system projection neuron axonogenesis | |
Biological Process | chordate embryonic development | |
Biological Process | eye development | |
Biological Process | protein phosphorylation | |
Biological Process | regulation of organelle organization |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMitogen-activated protein kinase
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Tetraodontiformes > Tetradontoidea > Tetraodontidae > Tetraodon
Accessions
- Primary accessionH3D1Z5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-34 | Disordered | ||||
Sequence: MADTSSAAIVGDSSSDGDAAPAAPAPGTVDGAPA | ||||||
Domain | 55-343 | Protein kinase | ||||
Sequence: YTNLSYIGEGAYGMVCSALDNTSNQRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDILRAQHIDSMRDVYIVQTLMETDLYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYSKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILSVLGTPSQEDLNCIINMKARNYLQSLPLKNRVPWERLYGKADSKALDLLDRMLTFNPIKRITVEEALAHPYL |
Sequence similarities
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length391
- Mass (Da)44,245
- Last updated2012-04-18 v1
- ChecksumEEEE5612E3ED3F28
Keywords
- Technical term