H3CWZ0 · H3CWZ0_TETNG
- ProteinGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids306 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H+
Cofactor
Pathway
Protein modification; protein glycosylation.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 72-74 | UDP-alpha-D-glucuronate (UniProtKB | ChEBI) | |||
Binding site | 103 | UDP-alpha-D-glucuronate (UniProtKB | ChEBI) | |||
Binding site | 140 | UDP-alpha-D-glucuronate (UniProtKB | ChEBI) | |||
Binding site | 145 | UDP-alpha-D-glucuronate (UniProtKB | ChEBI) | |||
Binding site | 168-170 | UDP-alpha-D-glucuronate (UniProtKB | ChEBI) | |||
Binding site | 170 | Mn2+ (UniProtKB | ChEBI) | |||
Site | 201 | Interaction with galactose moiety of substrate glycoprotein | |||
Active site | 256 | Proton donor/acceptor | |||
Binding site | 283-285 | UDP-alpha-D-glucuronate (UniProtKB | ChEBI) | |||
Site | 293 | Interaction with galactose moiety of substrate glycoprotein | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | Golgi membrane | |
Molecular Function | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity | |
Molecular Function | metal ion binding | |
Biological Process | carbohydrate metabolic process | |
Biological Process | chondroitin sulfate proteoglycan biosynthetic process | |
Biological Process | protein glycosylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Tetraodontiformes > Tetradontoidea > Tetraodontidae > Tetraodon
Accessions
- Primary accessionH3CWZ0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Single-pass type II membrane protein
Membrane ; Single-pass type II membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-25 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for glycosylation.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Glycosylation | 275 | N-linked (GlcNAc...) asparagine | |||
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length306
- Mass (Da)35,050
- Last updated2012-04-18 v1
- MD5 Checksum2D229906A2118666A767BD8AD1063A39
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
H3BXK7 | H3BXK7_TETNG | 304 |
Keywords
- Technical term