Essential maintenance is planned to begin on Tue Jan 28 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ during this time.

H2ZSX7 · H2ZSX7_LATCH

Function

Catalytic activity

  • D-serine(in) + L-alanine(out) + Na+(out) = D-serine(out) + L-alanine(in) + Na+(in)
  • D-serine(in) + L-glutamine(out) + Na+(out) = D-serine(out) + L-glutamine(in) + Na+(in)
  • L-glutamine(in) + L-glutamate(out) + Na+(out) + H+(out) = L-glutamine(out) + L-glutamate(in) + Na+(in) + H+(in)
  • L-glutamine(in) + L-alanine(out) + Na+(out) = L-glutamine(out) + L-alanine(in) + Na+(in)
  • L-asparagine(in) + L-glutamine(out) + Na+(out) = L-asparagine(out) + L-glutamine(in) + Na+(in)
  • L-asparagine(out) + L-glutamine(in) + Na+(out) = L-asparagine(in) + L-glutamine(out) + Na+(in)
  • L-glutamine(in) + L-methionine(out) + Na+(out) = L-glutamine(out) + L-methionine(in) + Na+(in)
  • L-serine(out) + L-glutamine(in) + Na+(out) = L-serine(in) + L-glutamine(out) + Na+(in)
  • L-threonine(out) + L-glutamine(in) + Na+(out) = L-threonine(in) + L-glutamine(out) + Na+(in)
  • L-valine(out) + L-glutamine(in) + Na+(out) = L-valine(in) + L-glutamine(out) + Na+(in)
  • L-serine(in) + L-glutamine(out) + Na+(out) = L-serine(out) + L-glutamine(in) + Na+(in)
  • L-threonine(in) + L-glutamine(out) + Na+(out) = L-threonine(out) + L-glutamine(in) + Na+(in)
  • iodide(out) = iodide(in)
  • nitrate(in) = nitrate(out)
  • thiocyanate(in) = thiocyanate(out)

GO annotations

AspectTerm
Cellular Componentmelanosome
Cellular Componentplasma membrane
Molecular Functionantiporter activity
Molecular FunctionL-aspartate transmembrane transporter activity
Molecular Functionmetal ion binding
Molecular Functionneutral L-amino acid transmembrane transporter activity
Molecular Functionsymporter activity
Biological ProcessL-aspartate import across plasma membrane

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Amino acid transporter

Gene names

    • Name
      SLC1A5

Organism names

  • Taxonomic identifier
  • Strain
    • Wild caught
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Coelacanthiformes > Coelacanthidae > Latimeria

Accessions

  • Primary accession
    H2ZSX7

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Melanosome
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane54-73Helical
Transmembrane93-114Helical
Transmembrane126-150Helical
Transmembrane256-274Helical
Transmembrane294-315Helical
Transmembrane327-353Helical
Transmembrane359-382Helical
Transmembrane402-427Helical
Transmembrane439-468Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region22-42Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    565
  • Mass (Da)
    60,563
  • Last updated
    2012-04-18 v1
  • MD5 Checksum
    36FD122EFFF19A6367CE34ABD8B6E014
EAKAMAEVDQKGASNGEVHMEELKDASGSTPAGGTKKGPVGKADRVKGCLRGNVLVILTVSGVVIGVLIGLGVRNVGLNRAQKIYFSFPGELLLRLLKMIIIPLVVCSLVAGAASLDPKDLGKLGGWAMLFFLITTLLASALGVTLALIIKPGVGAAAKTSLPGQEDTLPEPKEVVDSFLDLIRNIFPSNLVSAAFQSYATSYKLIREKKNITNESGVTNEAILIEKVWVVCTKAVIQLGDLAAIPIGVDADGMNILGLVVFAIVFGIALRKLGPEGENLVKFFNSFNEATMVLVSWIMWYAPFGIMFLVAGKIVEMEDVVVLFTSLGMYICCCLVGHFIHGLIVLPLIYFIITRKNPYRFLWGIFTALATAFGTSSSSATLPLMMKCVEENNGVSKQISRFILPIGATVNMDGAALFQCVAAVFIAQLNDYSLNFIQVIIILVTATASSVGAAGIPAGGVLTIAIILEAVGLPIDEISLILAVDWLIDRTCTVLNVEGDAFGAGLLQNFVDKQERRRKTEELTEVKTEKVEPVKLPGEEESPLIKKEVKATLERVNSCEKESVM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AFYH01111765
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AFYH01111766
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AFYH01111767
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AFYH01111768
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AFYH01111769
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AFYH01111770
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help