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H2YKR8 · H2YKR8_CIOSA

Function

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site, site.

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Type
IDPosition(s)Description
Binding site236Zn2+ (UniProtKB | ChEBI); catalytic
Active site237Proton acceptor
Binding site240Zn2+ (UniProtKB | ChEBI); catalytic
Binding site259Zn2+ (UniProtKB | ChEBI); catalytic
Site315Transition state stabilizer

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionmetalloaminopeptidase activity
Molecular Functionpeptide binding
Molecular Functionzinc ion binding
Biological Processpeptide catabolic process
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Aminopeptidase

Organism names

Accessions

  • Primary accession
    H2YKR8

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-129Aminopeptidase N-like N-terminal
Domain164-339Peptidase M1 membrane alanine aminopeptidase
Domain350-612ERAP1-like C-terminal

Sequence similarities

Belongs to the peptidase M1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    612
  • Mass (Da)
    69,524
  • Last updated
    2012-04-18 v1
  • MD5 Checksum
    B6BA3942DF85140F19FE7CBF24EC6547
YIVIKTTSPCEAGKMYTMFADDFTGELGDDLTGIYRSEYKNEAGVNRVIAISQMETTGARHTFPCFDEPAFKATFDFTLYHRSDQGFYAVANMPPIIILPFFIHQTEMIDTVLWNSTTFDTTYVMSTYLLAVTVSDFLYEPATSTAGTYIYARPETIKNNEGVFAAEVTPALLDTIATHYDIPYTLPKSDQMAVADFGAGAMENWGLVLYRETLLLFDENISSVHDKYSITQVIGHELGHQWFGNLVTCAWWNEIWLNEGFASYVQYIAVDGVKPEYKPWEIFIIDDLQIALSADAYSNSHPLVHPEGRFSSITYSKGASFLRMVQSFLGETTFTGALKVTTFTNSEDYILGNIKGNGFYRINYDLDMWGKLSLKLKDPSFKEIPVENRAQLVDDIFALSRSGRIDISLALDLATYMVNEDEYIPWQTFLDAMTYCEYMLGASPIYGDFSKYILDLVVPSIYADLGWDDSNTSDSALITRMIRGEAIDAACTYGNQDCIDNAVMLFDQWRNDTTTIISSTYRTDVFCTAIREGGLAEWDFAWEQYLLSQNAQFQSSLRYGLSCSKDAWVLNRYLEYAMDPTKVRKQDIQNTFSYIARQEYGKYTAWAFAMNN

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
H2YKR1H2YKR1_CIOSA865
H2YKR2H2YKR2_CIOSA851
H2YKR3H2YKR3_CIOSA841
H2YKR4H2YKR4_CIOSA711
H2YKR5H2YKR5_CIOSA812
H2YKR6H2YKR6_CIOSA429
H2YKR7H2YKR7_CIOSA853

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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