H2NJR7 · H2NJR7_PONAB

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Cellular Componentmembrane
Molecular Functioncytokine activity
Molecular Functionidentical protein binding
Molecular Functiontumor necrosis factor receptor binding
Biological Processbone resorption
Biological Processcalcium ion homeostasis
Biological Processcalcium-mediated signaling
Biological Processcellular response to leukemia inhibitory factor
Biological ProcessERK1 and ERK2 cascade
Biological Processimmune response
Biological ProcessJNK cascade
Biological Processmammary gland alveolus development
Biological Processmammary gland epithelial cell proliferation
Biological Processmonocyte chemotaxis
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processossification
Biological Processosteoclast development
Biological Processosteoclast proliferation
Biological Processparacrine signaling
Biological Processphosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processpositive regulation of bone resorption
Biological Processpositive regulation of canonical NF-kappaB signal transduction
Biological Processpositive regulation of corticotropin-releasing hormone secretion
Biological Processpositive regulation of ERK1 and ERK2 cascade
Biological Processpositive regulation of fever generation by positive regulation of prostaglandin secretion
Biological Processpositive regulation of gene expression
Biological Processpositive regulation of homotypic cell-cell adhesion
Biological Processpositive regulation of JNK cascade
Biological Processpositive regulation of MAP kinase activity
Biological Processpositive regulation of NF-kappaB transcription factor activity
Biological Processpositive regulation of osteoclast development
Biological Processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processpositive regulation of T cell activation
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processtooth eruption
Biological Processtumor necrosis factor-mediated signaling pathway

Keywords

  • Molecular function

Names & Taxonomy

Protein names

  • Recommended name
    Tumor necrosis factor ligand superfamily member

Gene names

    • Name
      TNFSF11
    • Synonyms
      TNLG6B
    • ORF names
      CR201_G0016794

Organism names

Accessions

  • Primary accession
    H2NJR7
  • Secondary accessions
    • A0A2J8VSR9
    • A0A663D782

Proteomes

Subcellular Location

Cell membrane
; Single-pass type II membrane protein
Secreted

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane49-70Helical

Keywords

Interaction

Subunit

Homotrimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-43Disordered
Compositional bias28-42Pro residues
Domain166-313THD

Sequence similarities

Belongs to the tumor necrosis factor family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    317
  • Mass (Da)
    35,461
  • Last updated
    2012-03-21 v1
  • Checksum
    769995108C0DBD6A
MRRASRDYTKYLRGSEEMGGGPGAPHEGPLHAQPPPAPHQPPAASRSMFVALLGLGLGQVVCSVALFLYFRAQMDPNRISEDGTHCIYRILRLHENADFQDTTLESQDTKLIPDSCRRIKQAFQGAVQKELQHIVGSQHIRAEKAMVDGSWLDLAKRSKLEAQPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISVEVSNPSLLDPDQDATYFGAFKVRDID

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias28-42Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LN874345
EMBL· GenBank· DDBJ
CTQ86110.1
EMBL· GenBank· DDBJ
mRNA
NDHI03003410
EMBL· GenBank· DDBJ
PNJ60569.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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