H2LW33 · H2LW33_ORYLA
- ProteinDisintegrin and metalloproteinase domain-containing protein 10
- Geneadam10a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids747 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 386 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 387 | ||||
Binding site | 390 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 396 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | synaptic membrane | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity involved in amyloid precursor protein catabolic process | |
Molecular Function | SH3 domain binding | |
Biological Process | membrane protein ectodomain proteolysis | |
Biological Process | Notch signaling pathway |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDisintegrin and metalloproteinase domain-containing protein 10
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Atherinomorphae > Beloniformes > Adrianichthyidae > Oryziinae > Oryzias
Accessions
- Primary accessionH2LW33
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 680-707 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-17 | ||||
Chain | PRO_5017338549 | 18-747 | Disintegrin and metalloproteinase domain-containing protein 10 | ||
Keywords
- PTM
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 223-459 | Peptidase M12B | |||
Domain | 460-554 | Disintegrin | |||
Region | 717-747 | Disordered | |||
Compositional bias | 724-747 | Polar residues | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length747
- Mass (Da)83,859
- Last updated2018-12-05 v2
- MD5 Checksum4291E7670C330AE5EDFA5F01AD9E5A6A
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
H2LW31 | H2LW31_ORYLA | adam10a | 692 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 724-747 | Polar residues | |||
Keywords
- Technical term