H2KQC7 · H2KQC7_CLOSI
- ProteinUridine 5'-monophosphate synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids530 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Pathway
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 292 | substrate | |||
Binding site | 314 | substrate | |||
Active site | 347 | For OMPdecase activity | |||
Active site | 349 | For OMPdecase activity | |||
Active site | 352 | For OMPdecase activity | |||
Binding site | 414 | substrate | |||
Binding site | 479 | substrate | |||
Binding site | 504 | substrate | |||
Binding site | 505 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | orotate phosphoribosyltransferase activity | |
Molecular Function | orotidine-5'-phosphate decarboxylase activity | |
Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | |
Biological Process | 'de novo' UMP biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridine 5'-monophosphate synthase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Platyhelminthes > Trematoda > Digenea > Opisthorchiida > Opisthorchiata > Opisthorchiidae > Clonorchis
Accessions
- Primary accessionH2KQC7
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 286-520 | Orotidine 5'-phosphate decarboxylase | |||
Sequence similarities
In the C-terminal section; belongs to the OMP decarboxylase family.
In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length530
- Mass (Da)58,388
- Last updated2012-03-21 v1
- MD5 Checksum9E072E03E333A40604E5AE626F371B8C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DF142989 EMBL· GenBank· DDBJ | GAA34819.2 EMBL· GenBank· DDBJ | Genomic DNA |