H2IT97 · H2IT97_RAHAC

Function

function

Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

Catalytic activity

Pathway

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
Glycolipid biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate: step 2/2.

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Molecular Functionhydrolase activity, acting on glycosyl bonds
Biological Process4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process
Biological Processlipid A biosynthetic process
Biological Processlipopolysaccharide biosynthetic process
Biological Processresponse to antibiotic
Biological Processxylan catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
  • EC number

Gene names

    • Name
      arnD
    • Ordered locus names
      Rahaq2_2850

Organism names

Accessions

  • Primary accession
    H2IT97

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-261NodB homology

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    299
  • Mass (Da)
    33,382
  • Last updated
    2012-03-21 v1
  • Checksum
    E0C1DF5351E79D90
MKKVGLRIDVDTWSGTREGVPQLLQTLANHKITASFFFSVGPDNMGRHLWRLLKPRFLWKMLRSNAASLYGWDILLAGTAWPGKLIARDLGYLMKETAKRGHEVGLHAWDHQGWQANVGKWSGEQMEEQIRLGLEALEKSLGHDVECSAVAGWRADERVIEVKERFHFYYNSDCRGTRPFLPVLENGTPGTVQIPVTLPTYDEVAGGEINADNFNDFILDAIAKDNGVPVYTIHAEVEGMSLAKQFDELLTRASAQGIQFCALGELLPQDLSTLPRGKVVRASFPGREGWLGCQQEGFS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003244
EMBL· GenBank· DDBJ
AEX52681.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp