H2IPD8 · H2IPD8_RAHAC

Function

function

Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.
Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site147Mg2+ (UniProtKB | ChEBI)
Binding site209Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentGram-negative-bacterium-type cell wall
Cellular Componentplasma membrane
Molecular Functionglycosyltransferase activity
Molecular Functionmagnesium ion binding
Molecular Functionmanganese ion binding
Molecular FunctionUDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity
Biological Processcell wall macromolecule biosynthetic process
Biological Processcell wall organization
Biological Processenterobacterial common antigen biosynthetic process
Biological ProcessO antigen biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
  • EC number
  • Alternative names
    • UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase
    • Undecaprenyl-phosphate GlcNAc-1-phosphate transferase

Gene names

    • Name
      wecA
    • Ordered locus names
      Rahaq2_3651

Organism names

Accessions

  • Primary accession
    H2IPD8

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-23Helical
Transmembrane44-62Helical
Transmembrane68-85Helical
Transmembrane92-113Helical
Transmembrane125-143Helical
Transmembrane155-174Helical
Transmembrane180-198Helical
Transmembrane205-227Helical
Transmembrane239-259Helical
Transmembrane287-307Helical
Transmembrane313-332Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 4 family. WecA subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    357
  • Mass (Da)
    39,476
  • Last updated
    2012-03-21 v1
  • Checksum
    94634A122E29479B
MYGFLFATPIICFIFLLAVRAISIKLKLVDKPDYRKKHSSNIPLVGGIAIYLTVVVINLLFFPSVAHNNAFLMSSFLLVCIGVLDDRYALSVFLRVIVQAAGAIIIMSDGVYISSFGNLWNNYELRLGILSFPVSLLAVWASVNAFNMIDGIDGLLGGLSILSFTGLAICFAVAGQMHMALYCQLFIAAIVPFILLNVSCSRLKIFMGDAGSTFLGFTVIWAIMLATGEYNAVMTPATAIWLIAVPLMDLVAVMFGRLIRRNSPFQPDRTHLHHVLINYGFSNKKTLSIILLVSFGMNVFGIGLNILKVNELLSLFLFCLIFVTYCLVRHWLVIHTKYSEVSPGDESHNKTIEISVQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003244
EMBL· GenBank· DDBJ
AEX53446.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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