H1KXL9 · H1KXL9_9EURY

Function

function

Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

coenzyme F430 (UniProtKB | Rhea| CHEBI:60540 )

Pathway

One-carbon metabolism; methyl-coenzyme M reduction; methane from methyl-coenzyme M: step 1/1.

GO annotations

AspectTerm
Molecular Functioncoenzyme-B sulfoethylthiotransferase activity
Biological Processmethanogenesis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methyl-coenzyme M reductase subunit beta
  • EC number
  • Alternative names
    • Coenzyme-B sulfoethylthiotransferase beta

Gene names

    • ORF names
      MetfoDRAFT_0542

Organism names

  • Taxonomic identifier
  • Strain
    • Mc-S-70
  • Taxonomic lineage
    Archaea > Euryarchaeota > Methanomada group > Methanococci > Methanococcales > Methanocaldococcaceae > Methanotorris

Accessions

  • Primary accession
    H1KXL9

Proteomes

Interaction

Subunit

Hexamer of two alpha, two beta, and two gamma chains.
MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-187Methyl-coenzyme M reductase beta subunit N-terminal
Domain189-437Methyl-coenzyme M reductase beta subunit C-terminal

Sequence similarities

Belongs to the methyl-coenzyme M reductase beta subunit family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    444
  • Mass (Da)
    47,497
  • Last updated
    2012-03-21 v1
  • Checksum
    6D6163917A4BBFB7
MVKYEDKICLYNAKGELVEENVPLEAISPLYNPTIQKLVKDIKRTVAVNLAGIENALKTGAVGGKACVIPGRTLDLPIVENAETIMEYVDKLLRISPDDDTSVKLINDGKQMAVQLPSKRLEVAAEYSISMLNTAMALKEAIIKTFDVDMFDAPMVHAAILGRYPQVPDYMGANIASLLGAPTNLEGLGYALRNIMVNHYVATTKKNIMNAVAFASIMEQTAMFEMGDAIGSFERLHLLGLAYQGLNADNLVIDLVKANGKNGTVGTVVASIVERALEDGVITEDKKMPSGFVLYKPVDVAKWNAYAAAGLVAAVIVNCGAARAAQNVASTILYYNDIIEYETGLPGVDFGRAEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPPVCAAMCVDAGTQMFSPEKTSALVGAVFSAIDEFREPLKYVIDGALAVKDKI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGJL01000010
EMBL· GenBank· DDBJ
EHP88092.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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