H1KV44 · H1KV44_METEX

Function

function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site161NADP+ (UniProtKB | ChEBI)
Binding site191substrate
Binding site195substrate
Binding site229substrate
Binding site248substrate
Active site253Proton acceptor
Binding site339substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number
  • Short names
    G6PD

Gene names

    • Name
      zwf
    • ORF names
      MetexDRAFT_6507

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 13060
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Methylobacteriaceae > Methylorubrum

Accessions

  • Primary accession
    H1KV44

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-200Glucose-6-phosphate dehydrogenase NAD-binding
Domain202-480Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    496
  • Mass (Da)
    54,755
  • Last updated
    2012-03-21 v1
  • Checksum
    CC0E98EBB410A3B1
MAGSRASRLGAGVGPKYPQVVVLVGATGDLAQRKLLPGLFHLFSAGFIPDLRIVGVSLDDIGVEAFREHAHKAIDRFFTRHAGDGEWAAFAERLDYVSLSAGAEALAAAVARAEAGLAQAHPGQESRRLHYLSVPPAAALTVVRLLAEAGLAAGSRIVMEKPFGTDLESAVALNDRLHEVFSEDQIFRIDHFLGKEPAQNILAFRFANGLFEPIWNRTFIDHVQIDVPETLGLGTRAAFYEATGAYRDMVVTHLFQILGFMAMEPPTSLEPGPISEEKNKVFRSMLPLDPREVVRGQYAGYRDEPGVDPQSDTETFIALKCRIDNWRWAGVPFFLRTGKRLAEGQRIISIAFREPPKSMFPVNSGVGAQGPDHLTFDLADASKMSLSFYGKRPGPGMRLDKLSLQFNMKDTGLMGEVLEAYERLILDAMRGDHTLFTTAEGIERLWEVSTPLLEAPPPVRLYAPGSWGPKSIHQLVAPQAWRLPFEREWRNTDEQG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGJK01000453
EMBL· GenBank· DDBJ
EHP76976.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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