H1A3H7 · H1A3H7_TAEGU

Function

Catalytic activity

Features

Showing features for binding site, active site.

111131002003004005006007008009001,0001,100
Type
IDPosition(s)Description
Binding site834-842ATP (UniProtKB | ChEBI)
Binding site861ATP (UniProtKB | ChEBI)
Binding site862ATP (UniProtKB | ChEBI)
Active site955Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoskeleton
Cellular Componentcytosol
Cellular Componentendomembrane system
Cellular Componentextrinsic component of cytoplasmic side of plasma membrane
Molecular FunctionATP binding
Molecular Functiongrowth hormone receptor binding
Molecular Functionnon-membrane spanning protein tyrosine kinase activity
Molecular Functionprotein phosphatase binding
Biological Processcell differentiation
Biological Processcell surface receptor signaling pathway via JAK-STAT
Biological Processgrowth hormone receptor signaling pathway via JAK-STAT
Biological Processinterleukin-15-mediated signaling pathway
Biological Processinterleukin-2-mediated signaling pathway
Biological Processinterleukin-4-mediated signaling pathway
Biological Processinterleukin-7-mediated signaling pathway
Biological Processinterleukin-9-mediated signaling pathway
Biological Processintracellular signal transduction
Biological Processnegative regulation of T-helper 17 cell lineage commitment
Biological Processpositive regulation of cell population proliferation
Biological Processprotein phosphorylation
Biological Processregulation of apoptotic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine-protein kinase
  • EC number

Gene names

    • Name
      JAK3

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia

Accessions

  • Primary accession
    H1A3H7

Proteomes

Subcellular Location

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain24-360FERM
Domain379-479SH2
Domain524-787Protein kinase
Domain828-1101Protein kinase

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,113
  • Mass (Da)
    124,653
  • Last updated
    2020-06-17 v2
  • Checksum
    B615684E0A28C8F2
MAPLGEETPLIGGRSCSLSSAESGTLQVFLYHRAPAPRRAPGSAAGTLSFTFGEYTAEELCVRAAKACGVLPVCHPLFALATEDLSCWFPPNHVFTVDESHSQVVVYRIRFFFPNWCGLGQSHRFQLLNGRASPVLDYPVIDYLFAQSRSDFIGGRVAVGLSLPTQEQCLSLAVLDMLRIAKEQRQSPAQVCSHVSYKSCLPAPLRSQIQQHNFVTRKRLRRRFGKSLRRLGGCHTDGPQLKLKYLLDLERLQRRRSEEIFHVRSPGSAAPIAIHVSGDGGVTWSCGGSESRQHFCDFPDIADISIKQAASRDGGPVENRLVTVTKADNRVLEVEFATLREARSFVALLDGYYRLTADAQHYFCREVAPPRLLEDLENQCHGPISAEFAVNKLEAAGGAPGLFLLRRSPQDFDSYLLTVCVQTRSGRDYKRCRIRRDEDGHLWLSGVARRFCSLRELLGTYGHRGLQAEGAPMRLEVACPPRPKEKSNLLIVRSGVPCPPGSPPAPQRRSLQQMMFHKIDPQSLTRGESLGQGSFTQIYKGVKREQDEEDGPRQTPVVLKVMDSSHRNCLESFLEAASTMSQLSCKHLVLLHGVSLGKDSVMVQEYVRHGPLDLYLRKNRGMVTTGWKLTVAKQLAYALNYLEDKKIPHGNVSAKKVLLAREGDTARGSPPFIKLNDPGVSVTVLARDMLVQRIPWVAPECVSNPGSLALPADKWGFGATLWEIFSGGNMPLSLLEPQRKLEFYQGCQQLPAPKWPELAVLVAQCMEYEPQRRPCFRALIRDLNSLITSDYELLSDLSPVDVTLRDGFWGHDSLAMSQDPEHFQERHLKYISLLGKGNFGSVELCRYDPLGDSTGELVAVKKLQQDSAKEIRDFEREIQILHSLQHDFIVRYRGVCYSRGMRGLRLVMEFLPNGCLRDFLQKNQPRLEHGTLLLYAWQICKGMEYLGAQRCVHRDLASRNILVESDSHVKIGDFGLAKLLPQDKDYYVVREPGQSPVFWYAPESLADNIFSCASDAWSFGVLLYELFTYSSKSRSPSEEFLRMMGTARPAQIICHLLELLKDNRRLPAPTGCPSEVYTLMLSCWAFAPGARPTFGELSPKIEALRDGRSKTRG

Keywords

Genome annotation databases

Similar Proteins

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