H1A377 · H1A377_TAEGU
- ProteinPhospholipase A2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids143 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H+
Cofactor
Note: Binds 1 Ca2+ ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 40 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 42 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 44 | Ca2+ (UniProtKB | ChEBI) | |||
Active site | 60 | ||||
Binding site | 61 | Ca2+ (UniProtKB | ChEBI) | |||
Active site | 110 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | calcium ion binding | |
Molecular Function | calcium-dependent phospholipase A2 activity | |
Molecular Function | phospholipid binding | |
Biological Process | arachidonic acid secretion | |
Biological Process | lipid catabolic process | |
Biological Process | negative regulation of T cell proliferation | |
Biological Process | phospholipid metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhospholipase A2
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia
Accessions
- Primary accessionH1A377
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-24 | ||||
Chain | PRO_5025714187 | 25-143 | Phospholipase A2 | ||
Disulfide bond | 41↔57 | ||||
Disulfide bond | 56↔116 | ||||
Disulfide bond | 62↔143 | ||||
Disulfide bond | 63↔109 | ||||
Disulfide bond | 90↔107 | ||||
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 14-137 | Phospholipase A2 | |||
Sequence similarities
Belongs to the phospholipase A2 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length143
- Mass (Da)15,320
- Last updated2020-06-17 v2
- Checksum5CACCE5AE85B7078
Keywords
- Technical term