H0Z182 · H0Z182_TAEGU

Function

Catalytic activity

  • Endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end-products.
    EC:3.1.21.1 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site.

128420406080100120140160180200220240260280
TypeIDPosition(s)Description
Active site100
Active site156

GO annotations

AspectTerm
Cellular Componentextracellular region
Cellular Componentnuclear envelope
Cellular Componentzymogen granule
Molecular Functiondeoxyribonuclease I activity
Molecular FunctionDNA binding
Biological ProcessDNA catabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Deoxyribonuclease

Gene names

    • Name
      DNASE1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia

Accessions

  • Primary accession
    H0Z182

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-22
ChainPRO_502538861223-284Deoxyribonuclease
Disulfide bond123↔126
Disulfide bond195↔231Essential for enzymatic activity

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain28-274Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the DNase I family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    284
  • Mass (Da)
    31,401
  • Last updated
    2020-06-17 v2
  • Checksum
    6475FEE6D6F32DDF
MATSRLVLSLLVTALLLHVATTLKIGAFNIKAFGDTKMSNQTVANIIISVLSEYDIVLVQEVRDADMSAVNYLMDQLNSAGKHPYSSLVSVPLGRTSYKEQYLFIYRSDMVSVLGSYYYDDGCESCGNDSFSREPFIVKFSSPTTQVQEFVLVPLHSEPSHAAQEIDALYDVYTDVINKWGTNDMIFLGDFNAGCSYVTSSQWPSIRLRSLPACEWLIPDSADTTVADTDCAYDRIVACGTALRQGTEPGSATINNFQQKFHLQMKDALAVSDHFPVEVTLKAH

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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