H0YQ82 · H0YQ82_TAEGU

Function

Catalytic activity

Features

Showing features for binding site, active site.

166850100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site395-403ATP (UniProtKB | ChEBI)
Binding site420ATP (UniProtKB | ChEBI)
Active site512Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentB cell receptor complex
Cellular Componentearly phagosome
Cellular Componentnucleus
Cellular ComponentT cell receptor complex
Molecular FunctionATP binding
Molecular Functionintegrin binding
Molecular Functioninterleukin-15 receptor binding
Molecular Functionnon-membrane spanning protein tyrosine kinase activity
Molecular Functionphosphatase binding
Molecular Functionphospholipase binding
Molecular Functionphosphotyrosine residue binding
Molecular Functionprotein kinase binding
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionscaffold protein binding
Molecular FunctionSH2 domain binding
Molecular FunctionToll-like receptor binding
Biological ProcessB cell differentiation
Biological ProcessB cell receptor signaling pathway
Biological Processbeta selection
Biological Processblood vessel morphogenesis
Biological Processcalcium-mediated signaling
Biological Processcellular response to lipid
Biological Processcellular response to low-density lipoprotein particle stimulus
Biological Processcellular response to molecule of fungal origin
Biological Processcollagen-activated tyrosine kinase receptor signaling pathway
Biological Processdefense response to bacterium
Biological Processgamma-delta T cell differentiation
Biological Processinnate immune response
Biological Processintegrin-mediated signaling pathway
Biological Processinterleukin-3-mediated signaling pathway
Biological Processleukocyte cell-cell adhesion
Biological Processleukotriene biosynthetic process
Biological Processlymph vessel development
Biological Processmacrophage activation involved in immune response
Biological Processmast cell degranulation
Biological Processneutrophil activation involved in immune response
Biological Processneutrophil chemotaxis
Biological Processpositive regulation of alpha-beta T cell differentiation
Biological Processpositive regulation of alpha-beta T cell proliferation
Biological Processpositive regulation of B cell differentiation
Biological Processpositive regulation of bone resorption
Biological Processpositive regulation of calcium-mediated signaling
Biological Processpositive regulation of cell adhesion mediated by integrin
Biological Processpositive regulation of cold-induced thermogenesis
Biological Processpositive regulation of gamma-delta T cell differentiation
Biological Processpositive regulation of granulocyte macrophage colony-stimulating factor production
Biological Processpositive regulation of interleukin-10 production
Biological Processpositive regulation of interleukin-12 production
Biological Processpositive regulation of interleukin-3 production
Biological Processpositive regulation of interleukin-4 production
Biological Processpositive regulation of interleukin-6 production
Biological Processpositive regulation of interleukin-8 production
Biological Processpositive regulation of killing of cells of another organism
Biological Processpositive regulation of MAPK cascade
Biological Processpositive regulation of mast cell cytokine production
Biological Processpositive regulation of mast cell degranulation
Biological Processpositive regulation of monocyte chemotactic protein-1 production
Biological Processpositive regulation of peptidyl-tyrosine phosphorylation
Biological Processpositive regulation of protein-containing complex assembly
Biological Processpositive regulation of receptor internalization
Biological Processpositive regulation of superoxide anion generation
Biological Processpositive regulation of TORC1 signaling
Biological Processpositive regulation of tumor necrosis factor production
Biological Processpositive regulation of type I interferon production
Biological Processprotein import into nucleus
Biological Processreceptor internalization
Biological Processregulation of arachidonic acid secretion
Biological Processregulation of ERK1 and ERK2 cascade
Biological Processregulation of neutrophil degranulation
Biological Processregulation of phagocytosis
Biological Processregulation of platelet aggregation
Biological Processregulation of tumor necrosis factor-mediated signaling pathway
Biological Processserotonin secretion by platelet
Biological Processstimulatory C-type lectin receptor signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine-protein kinase SYK
  • EC number

Gene names

    • Name
      SYK

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia

Accessions

  • Primary accession
    H0YQ82

Proteomes

Subcellular Location

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain32-124SH2
Domain185-276SH2
Domain389-668Protein kinase

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    668
  • Mass (Da)
    75,701
  • Last updated
    2020-06-17 v2
  • Checksum
    B3BF1E9CC851DA0F
MFLSRYSILGLLLGKEKAMASSTSNPANHLPYFFGNITREDAEEYLMQGGASDGLYLLRQSRNYLGGFTLSLAHGRKVHHYTIERELSGSYAIAGGKSHASPAELINYHSGEADGLICLLRKPFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSKNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLTIPCPQHGSENDNLGFNTHSSSGTLPKSWAGGGIISRLKSYTFPKAGSKKLQSAIGHPPEEAPFNPYVLQRNRGLAGAERGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMERPEVCPTEVYSLMKLCWTYKTVCEQFYESFNYTEAKAWTKKYTQGLLGLRAASFFPPK

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A674H2I4A0A674H2I4_TAEGUSYK606
A0A674HEC5A0A674HEC5_TAEGUSYK630
A0A674HBP8A0A674HBP8_TAEGUSYK639

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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