H0YPV2 · H0YPV2_TAEGU
- ProteinDual specificity protein phosphatase
- GeneDUSP1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids369 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 260 | Phosphocysteine intermediate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | MAP kinase tyrosine phosphatase activity | |
Molecular Function | MAP kinase tyrosine/serine/threonine phosphatase activity | |
Molecular Function | mitogen-activated protein kinase binding | |
Molecular Function | myosin phosphatase activity | |
Molecular Function | protein tyrosine/threonine phosphatase activity | |
Biological Process | cellular response to chemokine | |
Biological Process | endoderm formation | |
Biological Process | negative regulation of cell adhesion | |
Biological Process | negative regulation of cell population proliferation | |
Biological Process | negative regulation of MAP kinase activity | |
Biological Process | negative regulation of monocyte chemotaxis | |
Biological Process | negative regulation of p38MAPK cascade | |
Biological Process | peptidyl-serine dephosphorylation | |
Biological Process | peptidyl-threonine dephosphorylation | |
Biological Process | peptidyl-tyrosine dephosphorylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDual specificity protein phosphatase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia
Accessions
- Primary accessionH0YPV2
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 21-138 | Rhodanese | |||
Domain | 175-316 | Tyrosine-protein phosphatase | |||
Domain | 240-294 | Tyrosine specific protein phosphatases | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length369
- Mass (Da)39,975
- Last updated2020-06-17 v2
- Checksum4F034CD1A580B9CB
Keywords
- Technical term