H0YJJ9 · H0YJJ9_HUMAN

  • Protein
    non-specific serine/threonine protein kinase
  • Gene
    VRK1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Features

Showing features for binding site.

139450100150200250300350
TypeIDPosition(s)Description
Binding site71ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentmembrane
Cellular Componentnucleoplasm
Molecular FunctionATP binding
Molecular Functionprotein serine/threonine kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      VRK1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    H0YJJ9

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane359-376Helical

Keywords

  • Cellular component

Disease & Variants

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)13PRIDEPhosphoserine
Modified residue (large scale data)342PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain37-317Protein kinase

Sequence similarities

Belongs to the protein kinase superfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    394
  • Mass (Da)
    45,044
  • Last updated
    2021-06-02 v2
  • Checksum
    F022D372DB346E67
MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKVNFVIKLFFGLLVFIIAINTKRKYSSSSMKNNNRLHGN

Computationally mapped potential isoform sequences

There are 37 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q99986VRK1_HUMANVRK1396
H0YJF7H0YJF7_HUMANVRK1420
H0YJ50H0YJ50_HUMANVRK1228
A0A7P0T9E5A0A7P0T9E5_HUMANVRK1395
A0A7P0T9I1A0A7P0T9I1_HUMANVRK1372
A0A7P0T9T1A0A7P0T9T1_HUMANVRK1394
A0A7P0T8M0A0A7P0T8M0_HUMANVRK1101
A0A7P0T925A0A7P0T925_HUMANVRK1314
A0A7P0T8N0A0A7P0T8N0_HUMANVRK1356
A0A7P0T952A0A7P0T952_HUMANVRK1393
A0A7P0T977A0A7P0T977_HUMANVRK1362
A0A7P0T8Z5A0A7P0T8Z5_HUMANVRK199
A0A7P0T9C6A0A7P0T9C6_HUMANVRK1302
A0A7P0T9B1A0A7P0T9B1_HUMANVRK1172
A0A7P0T838A0A7P0T838_HUMANVRK1395
A0A7P0T824A0A7P0T824_HUMANVRK1444
A0A7P0T832A0A7P0T832_HUMANVRK1170
A0A7P0T833A0A7P0T833_HUMANVRK146
A0A7P0T814A0A7P0T814_HUMANVRK1249
A0A7P0TBB8A0A7P0TBB8_HUMANVRK1375
A0A7P0TBE4A0A7P0TBE4_HUMANVRK1413
A0A7P0TBI6A0A7P0TBI6_HUMANVRK1321
A0A7P0TA65A0A7P0TA65_HUMANVRK1393
A0A7P0TAA6A0A7P0TAA6_HUMANVRK1437
A0A7P0TAI5A0A7P0TAI5_HUMANVRK183
A0A7P0TB08A0A7P0TB08_HUMANVRK1244
A0A7P0TAS8A0A7P0TAS8_HUMANVRK1403
A0A7P0TB37A0A7P0TB37_HUMANVRK152
A0A7P0TB15A0A7P0TB15_HUMANVRK1394
A0A7P0TA07A0A7P0TA07_HUMANVRK172
A0A7P0TA16A0A7P0TA16_HUMANVRK1442
A0A7P0Z4P9A0A7P0Z4P9_HUMANVRK181
A0A7P0Z3Z7A0A7P0Z3Z7_HUMANVRK1395
A0A7P0Z445A0A7P0Z445_HUMANVRK1448
A0A7P0Z462A0A7P0Z462_HUMANVRK1395
A0A7P0Z4C8A0A7P0Z4C8_HUMANVRK1161
A0A7P0Z4A4A0A7P0Z4A4_HUMANVRK1366

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL133168
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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