H0YBU6 · H0YBU6_HUMAN
- ProteinRegulating synaptic membrane exocytosis 1
- GeneRIMS1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1038 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | small GTPase binding | |
Biological Process | exocytosis |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionH0YBU6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 989 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 22 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 302 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 305 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 455 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 551 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 573 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 600 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 657 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 677 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 753 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 762 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 796 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 832 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 835 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 836 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 959 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 1023 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 1025 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 1026 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 1029 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 1038 | PRIDE | Phosphoserine | ||||
Sequence: S |
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-126 | Disordered | ||||
Sequence: XYSAERTAETRAPGAKQLTNHSPPAPRHGPVPAEAPELKAQEPLRKQSRLDPSSAVLMRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRSKRGGKKRQMSVSSSEEEGVSTPEYTSCEDVELE | ||||||
Compositional bias | 56-71 | Basic and acidic residues | ||||
Sequence: VLMRKAKREKVETMLR | ||||||
Compositional bias | 72-86 | Polar residues | ||||
Sequence: NDSLSSDQSESVRPS | ||||||
Domain | 179-265 | PDZ | ||||
Sequence: RTTMPKDSGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSR | ||||||
Region | 272-306 | Disordered | ||||
Sequence: RIPESSHPPLESSSSSFESQKMERPSISVISPTSP | ||||||
Compositional bias | 278-304 | Polar residues | ||||
Sequence: HPPLESSSSSFESQKMERPSISVISPT | ||||||
Domain | 316-439 | C2 | ||||
Sequence: LPGQLSVKLWYDKVGHQLIVNVLQATDLPARVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKILEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWY | ||||||
Region | 443-624 | Disordered | ||||
Sequence: THDESSLPLPQPSPFMPRRHIHGESSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSARESKSTTLTVPEQQRTTHHRSRSVSPHRGNDQGKPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRTRDVDSQYLSEQDRMHRQRSPTQSPPADTSFSSRRGRQLPQVPVRS | ||||||
Compositional bias | 463-484 | Basic and acidic residues | ||||
Sequence: IHGESSSKKLQRSQRISDSDIS | ||||||
Compositional bias | 503-518 | Polar residues | ||||
Sequence: SARESKSTTLTVPEQQ | ||||||
Compositional bias | 519-538 | Basic and acidic residues | ||||
Sequence: RTTHHRSRSVSPHRGNDQGK | ||||||
Compositional bias | 567-596 | Basic and acidic residues | ||||
Sequence: HHDASRSPVDHRTRDVDSQYLSEQDRMHRQ | ||||||
Compositional bias | 597-624 | Polar residues | ||||
Sequence: RSPTQSPPADTSFSSRRGRQLPQVPVRS | ||||||
Compositional bias | 648-663 | Polar residues | ||||
Sequence: FKQTTGSGSSQELDRE | ||||||
Region | 648-668 | Disordered | ||||
Sequence: FKQTTGSGSSQELDREQYSKY | ||||||
Compositional bias | 705-721 | Polar residues | ||||
Sequence: LSSTSFMSEQSERPRGR | ||||||
Region | 705-740 | Disordered | ||||
Sequence: LSSTSFMSEQSERPRGRISSFTPKMQGRRMGTSGRS | ||||||
Region | 754-774 | Disordered | ||||
Sequence: LEHNDGSQSDTAVGTVGAGGK | ||||||
Compositional bias | 791-806 | Polar residues | ||||
Sequence: RSRSTSQLSQTESGHK | ||||||
Region | 791-822 | Disordered | ||||
Sequence: RSRSTSQLSQTESGHKKLKSTIQRSTETGMAA | ||||||
Domain | 884-1002 | C2 | ||||
Sequence: AMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWY |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length1,038
- Mass (Da)115,716
- Last updated2012-02-22 v1
- Checksum5936C8105B040113
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q86UR5 | RIMS1_HUMAN | RIMS1 | 1692 | ||
H0YBE7 | H0YBE7_HUMAN | RIMS1 | 610 | ||
A0A8V8TKU9 | A0A8V8TKU9_HUMAN | RIMS1 | 1515 | ||
E5RGM0 | E5RGM0_HUMAN | RIMS1 | 753 | ||
A0A0C4DFV1 | A0A0C4DFV1_HUMAN | RIMS1 | 740 |
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: X | ||||||
Compositional bias | 56-71 | Basic and acidic residues | ||||
Sequence: VLMRKAKREKVETMLR | ||||||
Compositional bias | 72-86 | Polar residues | ||||
Sequence: NDSLSSDQSESVRPS | ||||||
Compositional bias | 278-304 | Polar residues | ||||
Sequence: HPPLESSSSSFESQKMERPSISVISPT | ||||||
Compositional bias | 463-484 | Basic and acidic residues | ||||
Sequence: IHGESSSKKLQRSQRISDSDIS | ||||||
Compositional bias | 503-518 | Polar residues | ||||
Sequence: SARESKSTTLTVPEQQ | ||||||
Compositional bias | 519-538 | Basic and acidic residues | ||||
Sequence: RTTHHRSRSVSPHRGNDQGK | ||||||
Compositional bias | 567-596 | Basic and acidic residues | ||||
Sequence: HHDASRSPVDHRTRDVDSQYLSEQDRMHRQ | ||||||
Compositional bias | 597-624 | Polar residues | ||||
Sequence: RSPTQSPPADTSFSSRRGRQLPQVPVRS | ||||||
Compositional bias | 648-663 | Polar residues | ||||
Sequence: FKQTTGSGSSQELDRE | ||||||
Compositional bias | 705-721 | Polar residues | ||||
Sequence: LSSTSFMSEQSERPRGR | ||||||
Compositional bias | 791-806 | Polar residues | ||||
Sequence: RSRSTSQLSQTESGHK |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL034373 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL035633 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL160405 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL390056 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL445256 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL590011 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF458197 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF510957 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |