H0Y5B5 · H0Y5B5_HUMAN

  • Protein
    Polybromo 1
  • Gene
    PBRM1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleoplasm
Cellular ComponentRSC-type complex
Molecular Functionchromatin binding
Biological Processchromatin remodeling

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Polybromo 1

Gene names

    • Name
      PBRM1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    H0Y5B5

Proteomes

Organism-specific databases

Subcellular Location

Disease & Variants

Variants

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The viewer provides 2,383 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)75PRIDEPhosphoserine
Modified residue (large scale data)122PRIDEPhosphoserine
Modified residue (large scale data)245PRIDEPhosphothreonine
Modified residue (large scale data)247PRIDEPhosphoserine
Modified residue (large scale data)258PRIDEPhosphoserine
Modified residue (large scale data)260PRIDEPhosphoserine
Modified residue (large scale data)263PRIDEPhosphoserine
Modified residue (large scale data)295PRIDEPhosphotyrosine
Modified residue (large scale data)297PRIDEPhosphoserine
Modified residue (large scale data)299PRIDEPhosphoserine
Modified residue (large scale data)310PRIDEPhosphotyrosine
Modified residue (large scale data)315PRIDEPhosphoserine
Modified residue (large scale data)319PRIDEPhosphoserine
Modified residue (large scale data)442PRIDEPhosphoserine
Modified residue (large scale data)445PRIDEPhosphoserine
Modified residue (large scale data)446PRIDEPhosphoserine
Modified residue (large scale data)449PRIDEPhosphoserine
Modified residue (large scale data)451PRIDEPhosphothreonine
Modified residue (large scale data)453PRIDEPhosphoserine
Modified residue (large scale data)564PRIDEPhosphoserine
Modified residue (large scale data)595PRIDEPhosphoserine
Modified residue (large scale data)607PRIDEPhosphoserine
Modified residue (large scale data)640PRIDEPhosphoserine
Modified residue (large scale data)892PRIDEPhosphoserine
Modified residue (large scale data)893PRIDEPhosphoserine
Modified residue (large scale data)904PRIDEPhosphothreonine
Modified residue (large scale data)906PRIDEPhosphoserine
Modified residue (large scale data)910PRIDEPhosphoserine
Modified residue (large scale data)945PRIDEPhosphoserine
Modified residue (large scale data)1057PRIDEPhosphoserine

Keywords

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain8-78Bromo
Region99-121Disordered
Domain144-214Bromo
Domain344-414Bromo
Region431-466Disordered
Domain497-567Bromo
Compositional bias584-598Basic and acidic residues
Region584-605Disordered
Domain635-705Bromo
Domain776-821Bromo
Compositional bias861-891Basic and acidic residues
Region861-899Disordered
Domain914-1032BAH
Region1064-1085Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    1,085
  • Mass (Da)
    126,293
  • Last updated
    2012-02-22 v1
  • Checksum
    854E131E952806D5
IRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKRAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNL

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q86U86PB1_HUMANPBRM11689
C9J9L6C9J9L6_HUMANPBRM126
C9J409C9J409_HUMANPBRM143
C9J053C9J053_HUMANPBRM1118
E7EVG2E7EVG2_HUMANPBRM11460
C9JPI5C9JPI5_HUMANPBRM1230
C9JQF1C9JQF1_HUMANPBRM1152
C9JCJ2C9JCJ2_HUMANPBRM187
A0A9L9PXL4A0A9L9PXL4_HUMANPBRM11704

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias584-598Basic and acidic residues
Compositional bias861-891Basic and acidic residues
Non-terminal residue1085

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC104446
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC112215
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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