H0WG15 · H0WG15_OTOGA
- ProteinBis(monoacylglycero)phosphate synthase CLN5
- GeneCLN5
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids359 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity in vitro and most likely plays a role in protein S-depalmitoylation.
Catalytic activity
- 2 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) = 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)This reaction proceeds in the forward direction.
- 2 3-hexadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol) = 3-hexadecanoyl-sn-glycero-1-phospho-(3'-hexadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)This reaction proceeds in the forward direction.
- 2 3-octadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol) = 3-octadecanoyl-sn-glycero-1-phospho-(3'-octadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)This reaction proceeds in the forward direction.
- 2 3-tetradecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol) = 3-tetradecanoyl-sn-glycero-1-phospho-(3'-tetradecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)This reaction proceeds in the forward direction.
- 2 a 3-acyl-sn-glycero-1-phospho-(1'-sn-glycerol) = a 3-acyl-sn-glycero-1-phospho-(3'-acyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | endoplasmic reticulum | |
Cellular Component | Golgi apparatus | |
Cellular Component | lysosomal membrane | |
Cellular Component | perinuclear region of cytoplasm | |
Cellular Component | vacuolar lumen | |
Molecular Function | bis(monoacylglycero)phosphate synthase activity | |
Molecular Function | D-mannose binding | |
Molecular Function | hydrolase activity, acting on glycosyl bonds | |
Molecular Function | long-chain fatty acyl-CoA hydrolase activity | |
Biological Process | brain development | |
Biological Process | glycosylation | |
Biological Process | lysosomal lumen acidification | |
Biological Process | neurogenesis | |
Biological Process | retrograde transport, endosome to Golgi | |
Biological Process | signal peptide processing | |
Biological Process | visual perception |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBis(monoacylglycero)phosphate synthase CLN5
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Strepsirrhini > Lorisiformes > Galagidae > Otolemur
Accessions
- Primary accessionH0WG15
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length359
- Mass (Da)41,547
- Last updated2012-02-22 v1
- ChecksumB517F8A989164490
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAQR03067861 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |