Following spring viremia of carp virus infection DrIFNPhi1/3 and DrIRF1/3/7 transcripts are significantly induced in zebrafish tissues which correlates with the replication of spring viremia of carp virus. data provide evidence that fish and mammals have evolved a similar IRF-dependent regulatory mechanism fine-tuning IFN gene activation.
The miR-142a-3p regulates HSC formation and differentiation through the repression of interferon regulatory factor 7 (irf7)-mediated inflammation signaling.
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