H0WA27 · H0WA27_CAVPO
- ProteinMitogen-activated protein kinase
- GeneMAPK7
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids797 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Cofactor
Activity regulation
Activated by threonine and tyrosine phosphorylation.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 85 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMitogen-activated protein kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Hystricomorpha > Caviidae > Cavia
Accessions
- Primary accessionH0WA27
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-15 | Basic and acidic residues | |||
Region | 1-28 | Disordered | |||
Domain | 55-337 | Protein kinase | |||
Region | 392-719 | Disordered | |||
Compositional bias | 419-454 | Pro residues | |||
Compositional bias | 496-535 | Basic and acidic residues | |||
Compositional bias | 568-587 | Polar residues | |||
Compositional bias | 613-631 | Pro residues | |||
Compositional bias | 635-649 | Polar residues | |||
Compositional bias | 665-682 | Pro residues | |||
Compositional bias | 683-703 | Polar residues | |||
Sequence similarities
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length797
- Mass (Da)86,743
- Last updated2017-11-22 v2
- ChecksumE5FE8F2897A4E28A
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A286XH34 | A0A286XH34_CAVPO | MAPK7 | 728 | ||
A0A286XHP6 | A0A286XHP6_CAVPO | MAPK7 | 350 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-15 | Basic and acidic residues | |||
Compositional bias | 419-454 | Pro residues | |||
Compositional bias | 496-535 | Basic and acidic residues | |||
Compositional bias | 568-587 | Polar residues | |||
Compositional bias | 613-631 | Pro residues | |||
Compositional bias | 635-649 | Polar residues | |||
Compositional bias | 665-682 | Pro residues | |||
Compositional bias | 683-703 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAKN02046455 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |