H0GPA5 · H0GPA5_SACCK
- ProteinFatty acid synthase subunit alpha
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1832 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- a (3R)-hydroxyacyl-[ACP] + NADP+ = a 3-oxoacyl-[ACP] + NADPH + H+
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 1250 | For beta-ketoacyl synthase activity | |||
Binding site | 1717 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 1717-1719 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 1718 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 1719 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 1743 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 1753 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 1762-1778 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 1786-1789 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 1816-1818 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 1817 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 1818 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | fatty acid synthase complex | |
Molecular Function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity | |
Molecular Function | 3-oxoacyl-[acyl-carrier-protein] synthase activity | |
Molecular Function | fatty acid synthase activity | |
Molecular Function | fatty-acyl-CoA synthase activity | |
Molecular Function | holo-[acyl-carrier-protein] synthase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | long-chain fatty acid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFatty acid synthase subunit alpha
- EC number
Including 2 domains:
- Recommended name3-oxoacyl-[acyl-carrier-protein] reductase
- EC number
- Recommended name3-oxoacyl-[acyl-carrier-protein] synthase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionH0GPA5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 125 | O-(pantetheine 4'-phosphoryl)serine | |||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 37-65 | Disordered | |||
Domain | 90-165 | Carrier | |||
Domain | 1068-1602 | Ketosynthase family 3 (KS3) | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,832
- Mass (Da)200,769
- Last updated2012-02-22 v1
- MD5 ChecksumDC741EBE6F255F9F2736CA93FC2F364E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGVY01000049 EMBL· GenBank· DDBJ | EHN04224.1 EMBL· GenBank· DDBJ | Genomic DNA |