H0FCA1 · H0FCA1_9BURK

  • Protein
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
  • Gene
    glmS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site.

161050100150200250300350400450500550600
TypeIDPosition(s)Description
Active site2Nucleophile; for GATase activity
Active site605For Fru-6P isomerization activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncarbohydrate derivative binding
Molecular Functionglutamine-fructose-6-phosphate transaminase (isomerizing) activity
Biological Processcarbohydrate derivative biosynthetic process
Biological Processcarbohydrate metabolic process
Biological Processglutamine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
  • EC number
  • Alternative names
    • D-fructose-6-phosphate amidotransferase
    • GFAT
    • Glucosamine-6-phosphate synthase
    • Hexosephosphate aminotransferase
    • L-glutamine--D-fructose-6-phosphate amidotransferase

Gene names

    • Name
      glmS
    • ORF names
      KYC_22051

Organism names

Accessions

  • Primary accession
    H0FCA1

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine.

TypeIDPosition(s)Description
Initiator methionine1Removed

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-221Glutamine amidotransferase type-2
Domain286-426SIS
Domain459-600SIS

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    610
  • Mass (Da)
    66,876
  • Last updated
    2012-02-22 v1
  • Checksum
    85A6E3C47FB0C7A7
MCGIVGAVAQRDITPILVEGLKRLEYRGYDSCGVAVYADGHLRRTRSTQRVAELGEQIAQDKISGFTGIAHTRWATHGVPATHNAHPHFSHLGNDEPRIALVHNGIIENHDELRAELQAVGYVFESQTDTEVIAHLVNHLYAGDLFEAVQNAVRRLHGAYAIAVFCRDEPHRVVGARQGSPLVVGVGQNENFLASDALALAGTTDQIIYLEDGDVVDLQLSRVWIVDAAGKNVEREVHTVHVHTGAAELGPYRHYMQKEIFEQPRAVGDTLQDIEAITPELFGDGAYKIFKDIDSLLILACGTSYYAGLTAKYWIESIAKIPVAVEIASEYRYRDSVPNPRSLVVTISQSGETADTLAALKHARSLGMEHTLTICNVSTSAMVRECKLSYITRAGVEIGVASTKAFTTQLTALFLLTLTLAQVRGRLTDEQEAEHLKALRHLPAAIGSVLALEPQIMAWADRFASKENALFLGRGMHYPIALEGALKLKEISYIHAEAYPAGELKHGPLALVTEHMPVVTIAPKDELLEKLKSNMQEVRARGGELYVFADADSKIQSAEGMHVIRMPEHYGKLSPILHTVPLQLLSYHTACARGTDVDKPRNLAKSVTVE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGUF01000071
EMBL· GenBank· DDBJ
EHK64070.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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