H0FCA1 · H0FCA1_9BURK
- ProteinGlutamine--fructose-6-phosphate aminotransferase [isomerizing]
- GeneglmS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids610 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
Catalytic activity
- D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 2 | Nucleophile; for GATase activity | ||||
Sequence: C | ||||||
Active site | 605 | For Fru-6P isomerization activity | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | carbohydrate derivative binding | |
Molecular Function | glutamine-fructose-6-phosphate transaminase (isomerizing) activity | |
Biological Process | carbohydrate derivative biosynthetic process | |
Biological Process | carbohydrate metabolic process | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamine--fructose-6-phosphate aminotransferase [isomerizing]
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Alcaligenaceae > Achromobacter
Accessions
- Primary accessionH0FCA1
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for initiator methionine.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Initiator methionine | 1 | Removed | ||||
Sequence: M |
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-221 | Glutamine amidotransferase type-2 | ||||
Sequence: CGIVGAVAQRDITPILVEGLKRLEYRGYDSCGVAVYADGHLRRTRSTQRVAELGEQIAQDKISGFTGIAHTRWATHGVPATHNAHPHFSHLGNDEPRIALVHNGIIENHDELRAELQAVGYVFESQTDTEVIAHLVNHLYAGDLFEAVQNAVRRLHGAYAIAVFCRDEPHRVVGARQGSPLVVGVGQNENFLASDALALAGTTDQIIYLEDGDVVDLQLS | ||||||
Domain | 286-426 | SIS | ||||
Sequence: AYKIFKDIDSLLILACGTSYYAGLTAKYWIESIAKIPVAVEIASEYRYRDSVPNPRSLVVTISQSGETADTLAALKHARSLGMEHTLTICNVSTSAMVRECKLSYITRAGVEIGVASTKAFTTQLTALFLLTLTLAQVRGR | ||||||
Domain | 459-600 | SIS | ||||
Sequence: WADRFASKENALFLGRGMHYPIALEGALKLKEISYIHAEAYPAGELKHGPLALVTEHMPVVTIAPKDELLEKLKSNMQEVRARGGELYVFADADSKIQSAEGMHVIRMPEHYGKLSPILHTVPLQLLSYHTACARGTDVDKP |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length610
- Mass (Da)66,876
- Last updated2012-02-22 v1
- Checksum85A6E3C47FB0C7A7
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGUF01000071 EMBL· GenBank· DDBJ | EHK64070.1 EMBL· GenBank· DDBJ | Genomic DNA |