G9NLP8 · G9NLP8_HYPAI
- ProteinFerulic acid decarboxylase 1
- GeneFDC1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids512 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.
Catalytic activity
- (E)-4-coumarate + H+ = 4-vinylphenol + CO2
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 178 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 178-183 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 181 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 183 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 200 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 200-201 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 201 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 201 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 243 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 243 | prenyl-FMN (UniProtKB | ChEBI) | |||
Active site | 292 | Proton donor | |||
Binding site | 401 | prenyl-FMN (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | carboxy-lyase activity | |
Molecular Function | metal ion binding | |
Biological Process | cinnamic acid catabolic process | |
Biological Process | ferulate metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFerulic acid decarboxylase 1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Hypocreaceae > Trichoderma
Accessions
- Primary accessionG9NLP8
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 24-113 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like N-terminal | |||
Domain | 128-328 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase-likw Rift-related | |||
Domain | 335-470 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like C-terminal | |||
Sequence similarities
Belongs to the UbiD family. UbiD-like/FDC subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length512
- Mass (Da)55,933
- Last updated2012-02-22 v1
- MD5 Checksum9835458749CCD9D757C16901DAA00C9C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ABDG02000018 EMBL· GenBank· DDBJ | EHK48809.1 EMBL· GenBank· DDBJ | Genomic DNA |