G9N4A3 · VIRJ_HYPVG
- ProteinGlutamine--tRNA ligase protein virJ
- GenevirJ
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids646 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Glutamine--tRNA ligase; part of the gene cluster that mediates the biosynthesis of virensols and trichoxide, fungal natural products that contain or are derived from a salicylaldehyde core (PubMed:31790246).
VirJ does not seem to play any role in virensols and trichoxide biosynthesis (PubMed:31790246).
VirJ does not seem to play any role in virensols and trichoxide biosynthesis (PubMed:31790246).
Catalytic activity
- ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 99-101 | ATP (UniProtKB | ChEBI) | ||||
Sequence: EPN | ||||||
Binding site | 105-111 | ATP (UniProtKB | ChEBI) | ||||
Sequence: HLGHAKA | ||||||
Binding site | 147 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 296 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 315 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 344-345 | ATP (UniProtKB | ChEBI) | ||||
Sequence: RL | ||||||
Binding site | 352-354 | ATP (UniProtKB | ChEBI) | ||||
Sequence: MSK |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | glutamine-tRNA ligase activity | |
Biological Process | glutaminyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamine--tRNA ligase protein virJ
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Hypocreaceae > Trichoderma
Accessions
- Primary accessionG9N4A3
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000449288 | 1-646 | Glutamine--tRNA ligase protein virJ | |||
Sequence: MADAVAEAVAKLVLDDETGEMVTKNELKKRIQKRARKAAAAANRSNAQQEKGNKPAANKPAAKPEERVIDPDAMFKQGFLGDVFKLRPEESVVTRFPPEPNGYLHLGHAKAIAVNFGFAKYHGGRTQQQLDGQINYIPTDVADSRFDDTNPDAEKGEYFVAIEDTIRWLGFTPSEITYASDNYQRMYDLAEELIKMEKAYVCHCDDVETKKQRGGEDGLFPRYRCEHAKQDVETNLKKFRGMRDGEYAPRSAWLRMKQDIENNPNPQMWDLAAYRIPKDQEPHFRTGTKWRIYPTYDFAHCLCDSFEGITHSLCTTEFIMSRESYEWLNKLLVEFQPMQREYGRLNLSGTIMSKRGLRTLIENNVVRGWDDPRLYTIKGIRRRGIPPGALLSFIYELGVTTSITQVSIKRFEQSIRVYLEKTVPRLMLVLDPVPVVIEDGEEQDLDIPFSPKDPKLGSHTIRLTKTVYIDRSDFREVDSKDYFRLAPGKTVGLLNVPYPIKAVSFTKDETTGAIKEIKAVYDKEGKKPKTYIQWVPEGSLPAEVRIHEALFKSDSPGSAPGGLLSDVNPNSETIWPNALIETGFHEVKRRAPWPEAEGEKTGEFHPETVRFQAMRVAYFALDSDSTDEKIVLNRIVPLKEDSGKSS |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 25-65 | Disordered | ||||
Sequence: NELKKRIQKRARKAAAAANRSNAQQEKGNKPAANKPAAKPE | ||||||
Motif | 98-108 | 'HIGH' region | ||||
Sequence: PEPNGYLHLGH | ||||||
Motif | 351-355 | 'KMSKS' region | ||||
Sequence: IMSKR |
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length646
- Mass (Da)73,489
- Last updated2012-02-22 v1
- Checksum1BDA6736A994F91E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ABDF02000086 EMBL· GenBank· DDBJ | EHK18429.1 EMBL· GenBank· DDBJ | Genomic DNA |