G9KFT1 · G9KFT1_MUSPF

Function

Catalytic activity

Features

Showing features for binding site, active site, site.

110951002003004005006007008009001,000
Type
IDPosition(s)Description
Binding site572Mg2+ (UniProtKB | ChEBI)
Binding site599-607ATP (UniProtKB | ChEBI)
Binding site600-607ATP (UniProtKB | ChEBI)
Binding site627ATP (UniProtKB | ChEBI)
Binding site675-681ATP (UniProtKB | ChEBI)
Active site824Proton acceptor
Binding site828ATP (UniProtKB | ChEBI)
Binding site829Mg2+ (UniProtKB | ChEBI)
Binding site842Mg2+ (UniProtKB | ChEBI)
Site968Important for interaction with phosphotyrosine-binding proteins

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionplatelet-derived growth factor alpha-receptor activity
Molecular Functionplatelet-derived growth factor binding
Biological Processchemotaxis
Biological Processembryonic cranial skeleton morphogenesis
Biological Processpositive regulation of kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Platelet-derived growth factor receptor alpha
  • EC number
  • Alternative names
    • Alpha platelet-derived growth factor receptor
    • Alpha-type platelet-derived growth factor receptor

Organism names

Accessions

  • Primary accession
    G9KFT1

Subcellular Location

Cell membrane
; Single-pass type I membrane protein
Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane525-549Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-23
ChainPRO_500352304024-1095Platelet-derived growth factor receptor alpha
Disulfide bond49↔100
Disulfide bond150↔189
Disulfide bond235↔290
Disulfide bond435↔501

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain1-113Ig-like
Domain202-306Ig-like
Domain593-960Protein kinase
Region1024-1095Disordered
Compositional bias1035-1050Basic and acidic residues
Compositional bias1051-1066Polar residues

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    1,095
  • Mass (Da)
    123,412
  • Last updated
    2012-02-22 v1
  • Checksum
    D20831D6E6F73C51
MGTSLVALLILGCLLPGPGLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMSEEENPNVEIRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTEEMELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEEDDSAIIPCRTTDPETPVTLISSDGVVHASYDSRQGFNGTFSVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEVKEMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPKISWLKDNLTLIENLTEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDLVDDHHGTTGGQTVRCTAEGTPRPDIEWMVCKDIKKCNNETSWAILASNISNIITEVHPRDRSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDNFLSRHPEKPKKELDIFGLNPADDSTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKRPASYKKKSVLDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDADNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL

Features

Showing features for non-terminal residue, compositional bias.

Type
IDPosition(s)Description
Non-terminal residue1
Compositional bias1035-1050Basic and acidic residues
Compositional bias1051-1066Polar residues
Non-terminal residue1095

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JP015158
EMBL· GenBank· DDBJ
AES03756.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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