G9GCM3 · G9GCM3_9BACT
- ProteinD-alanine--D-alanine ligase
- GenevanA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids347 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation.
Catalytic activity
- 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + phosphate + H+
Cofactor
Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Binds 2 magnesium or manganese ions per subunit.
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 16 | ||||
Binding site | 134 | ATP (UniProtKB | ChEBI) | |||
Binding site | 170-172 | ATP (UniProtKB | ChEBI) | |||
Active site | 178 | ||||
Binding site | 178-179 | ATP (UniProtKB | ChEBI) | |||
Binding site | 208-215 | ATP (UniProtKB | ChEBI) | |||
Binding site | 293 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 305-306 | ATP (UniProtKB | ChEBI) | |||
Binding site | 306 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 306 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 308 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Active site | 317 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | D-alanine-D-alanine ligase activity | |
Molecular Function | metal ion binding | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameD-alanine--D-alanine ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > environmental samples
Accessions
- Primary accessionG9GCM3
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length347
- Mass (Da)37,378
- Last updated2012-02-22 v1
- MD5 Checksum2E35D1770614FD1CBF0E58716FBD75CD
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JN316578 EMBL· GenBank· DDBJ | AEU25611.1 EMBL· GenBank· DDBJ | Genomic DNA |