G9G9W6 · G9G9W6_CARAU

Function

function

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular FunctionJUN kinase activity
Molecular Functionprotein serine kinase activity
Biological Processrhythmic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Stress-activated protein kinase JNK
  • EC number

Gene names

    • Name
      JNKa

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Cyprinidae > Cyprininae > Carassius

Accessions

  • Primary accession
    G9G9W6

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain26-321Protein kinase
Region378-427Disordered
Compositional bias382-419Polar residues

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    427
  • Mass (Da)
    48,366
  • Last updated
    2012-02-22 v1
  • Checksum
    7ABB805E1CC54DDD
MNKNKREKEFYSVDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHNLERNVAIKKLSRPFQNQTHAKRAYRELVLMKYVNHKNIIGLLNVFTSQKTFDEFQDVYLVMELMDANLCQVIQMELDHERLSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGLLMTPYVVTRYYRAPEVILGMGYQANVDVWSVGCIMAEMVRGSVLFPGSDHIDQWNKVIEQLGTPSQEFMMKLNQSVRTYVENRPRYTGYSFEKLFPDVLFPADSENNKLKASQARDLLSKMLVIDASKRISVDEALRHPYINVWYDPAEVEAPPPLIIDKQLDEREHTVEEWKELIYKEVLDWEERVKNGVIRGQPSPIGAAVINGSPQPSSSSSINDVSSMSTEPTVASDTDSSLEASAGPLSCCR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias382-419Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JN257261
EMBL· GenBank· DDBJ
AET86806.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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