G8JYT2 · G8JYT2_RHOFA
- ProteinArgininosuccinate synthase
- GeneargG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids395 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-citrulline + L-aspartate + ATP = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H+
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 6-14 | ATP (UniProtKB | ChEBI) | |||
Binding site | 33 | ATP (UniProtKB | ChEBI) | |||
Binding site | 84 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 114 | ATP (UniProtKB | ChEBI) | |||
Binding site | 116 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 120 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 120 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 121 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 124 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 173 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 182 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 258 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 270 | L-citrulline (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | argininosuccinate synthase activity | |
Molecular Function | ATP binding | |
Biological Process | arginine biosynthetic process | |
Biological Process | argininosuccinate metabolic process | |
Biological Process | urea cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameArgininosuccinate synthase
- EC number
- Alternative names
Gene names
Encoded on
- Plasmid pFiD188
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Nocardiaceae > Rhodococcoides
Accessions
- Primary accessionG8JYT2
Subcellular Location
Interaction
Subunit
Homotetramer.
Structure
Sequence
- Sequence statusComplete
- Length395
- Mass (Da)42,769
- Last updated2012-01-25 v1
- MD5 Checksum70BF166F29D2D36D7E7D1367EBE43B03
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JN093097 EMBL· GenBank· DDBJ | AET25203.1 EMBL· GenBank· DDBJ | Genomic DNA |