G8JY36 · G8JY36_CAEEL

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 3 Ca2+ ions per subunit. The ions are bound to the C2 domain.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site233Ca2+ 1 (UniProtKB | ChEBI)
Binding site234Ca2+ 1 (UniProtKB | ChEBI)
Binding site240Ca2+ 1 (UniProtKB | ChEBI)
Binding site242a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) (UniProtKB | ChEBI)
Binding site293a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) (UniProtKB | ChEBI)
Binding site294Ca2+ 1 (UniProtKB | ChEBI)
Binding site295Ca2+ 1 (UniProtKB | ChEBI)
Binding site296Ca2+ 1 (UniProtKB | ChEBI)
Binding site299Ca2+ 1 (UniProtKB | ChEBI)
Binding site300Ca2+ 1 (UniProtKB | ChEBI)
Binding site302Ca2+ 1 (UniProtKB | ChEBI)
Binding site399-407ATP (UniProtKB | ChEBI)
Binding site422ATP (UniProtKB | ChEBI)
Active site517Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentmembrane
Cellular Componentneuron projection
Cellular Componentneuronal cell body
Molecular FunctionATP binding
Molecular Functioncalcium,diacylglycerol-dependent serine/threonine kinase activity
Molecular Functiondiacylglycerol-dependent serine/threonine kinase activity
Molecular Functionprotein serine kinase activity
Molecular Functionzinc ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein kinase C
  • EC number

Gene names

    • Name
      pkc-2
    • ORF names
      CELE_E01H11.1
      , E01H11.1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    G8JY36

Proteomes

Organism-specific databases

PTM/Processing

Keywords

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain83-133Phorbol-ester/DAG-type
Domain148-198Phorbol-ester/DAG-type
Domain205-323C2
Region357-378Disordered
Domain393-654Protein kinase
Domain655-725AGC-kinase C-terminal

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    725
  • Mass (Da)
    82,408
  • Last updated
    2012-01-25 v1
  • Checksum
    9EA97D05B44201F3
MHRSDESRMSFEHRSVVRLFSNSSTTSNGSRKTSVPSAVLASAPLMSAAIGDGLGTQLSQRIEGKAFVRRGALRQKNVHEIKSHKFIARFFKQPTFCSHCKDFLWGITKQGFQCQVCTLVVHKRCHEFVNFACPGADKGVDTDDPRQQHKWKVQTYSSPTFCDHCGSLLYGILHQGMKCQSCDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAASGWYKLLSAEEGEFYNINITPEYDEDMEKVRKKMNENFITRDNSSSKPKDPAAPRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKSADDTSNFDSEFTHEVPKLTPIDRLFLMNLDQTEFEGFSFVNPEYVQEC

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P90980KPC2_CAEELpkc-2682
A0A4V6M3D7A0A4V6M3D7_CAEELpkc-2751
A0A4V0IKF6A0A4V0IKF6_CAEELpkc-2727

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284606
EMBL· GenBank· DDBJ
CCD65291.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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