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G8B6M3 · G8B6M3_CANPC

Function

function

ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
RNA helicase.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentnuclear envelope
Cellular Componentnucleolus
Cellular Componentpreribosome, large subunit precursor
Cellular Componentsmall-subunit processome
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionidentical protein binding
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Biological Processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological ProcesssnoRNA release from pre-rRNA

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent RNA helicase
  • EC number

Gene names

    • Ordered locus names
      CPAR2_101430

Organism names

Accessions

  • Primary accession
    G8B6M3

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain, motif.

Type
IDPosition(s)Description
Compositional bias1-33Basic and acidic residues
Region1-110Disordered
Compositional bias34-56Acidic residues
Compositional bias73-90Basic and acidic residues
Domain112-140DEAD-box RNA helicase Q
Motif112-140Q motif
Domain143-319Helicase ATP-binding
Domain333-503Helicase C-terminal

Domain

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similarities

Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    578
  • Mass (Da)
    64,805
  • Last updated
    2012-01-25 v1
  • MD5 Checksum
    6FA3622CBB4E2942870207ECA44CD4DE
MAKHSTDKKTVRKSSLESTKHTKKRTRNESESDSDSENEVDIDTEKAVDQLDDEFDEVAGLLGQNIQDPEAKAVNKKQAKDEKRLQELTKAKVVDSSNNDNVDDDDESKDNYSFEKADFSEPTMKAIREMGFTKMTKVQAKTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELMYSLKIKPRNGTAVIIITPTRELALQIFGVARQLMEHHSQTCGIVIGGADRRQEATKLAKGVNLLVATPGRLLDHLKNTQGFVFSNLKALIIDEADRILEIGFEEEMKQIIKILPNEDRQTMLFSATQTTKVEDLARISLRPGPLYINVVSERDVSTADGLEQGYVVCDSDKRFLLLFSFLKRNVKKKIIVFLSSCNSVKFYSELLNYIDLPVLDLHGKQKQQKRTNTFFEFCNAKQGILVCTDVAARGLDIPAVDWIVQFDPPDDPRDYIHRVGRTARGTQGKGKSLMFLTPSELGFLRYLKAANVPLNEYEFPANKIANVQSQLTKLIKTNYLLHQSAKDGYRAYLQAYASHSLKTVYQIDKLDLVKVGKSFGFDVPPKVNITIGASGKSIEKKHKKQKRDKK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-33Basic and acidic residues
Compositional bias34-56Acidic residues
Compositional bias73-90Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HE605203
EMBL· GenBank· DDBJ
CCE40105.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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