G8B6M3 · G8B6M3_CANPC
- ProteinATP-dependent RNA helicase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids578 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
RNA helicase.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nuclear envelope | |
Cellular Component | nucleolus | |
Cellular Component | preribosome, large subunit precursor | |
Cellular Component | small-subunit processome | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | identical protein binding | |
Molecular Function | RNA binding | |
Molecular Function | RNA helicase activity | |
Biological Process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | |
Biological Process | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | |
Biological Process | snoRNA release from pre-rRNA |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent RNA helicase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Debaryomycetaceae > Candida/Lodderomyces clade > Candida
Accessions
- Primary accessionG8B6M3
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain, motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-33 | Basic and acidic residues | |||
Region | 1-110 | Disordered | |||
Compositional bias | 34-56 | Acidic residues | |||
Compositional bias | 73-90 | Basic and acidic residues | |||
Domain | 112-140 | DEAD-box RNA helicase Q | |||
Motif | 112-140 | Q motif | |||
Domain | 143-319 | Helicase ATP-binding | |||
Domain | 333-503 | Helicase C-terminal | |||
Domain
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence similarities
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length578
- Mass (Da)64,805
- Last updated2012-01-25 v1
- MD5 Checksum6FA3622CBB4E2942870207ECA44CD4DE
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-33 | Basic and acidic residues | |||
Compositional bias | 34-56 | Acidic residues | |||
Compositional bias | 73-90 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
HE605203 EMBL· GenBank· DDBJ | CCE40105.1 EMBL· GenBank· DDBJ | Genomic DNA |