G7X8S6 · NIT2_ASPKW

Function

function

Nitrilase that hydrolyzes preferentially phenylacetonitrile and (R,S)-mandelonitrile. Also acts on dinitriles like phenylenediacetonitriles (PDAs) 1,2-PDA, 1,3-PDA, and 1,4-PDA, and cyanophenyl acetonitriles (CPAs) 2-CPA and 4-CPA.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site45Proton acceptor
Active site125
Active site160Nucleophile

GO annotations

AspectTerm
Molecular Functionarylacetonitrilase activity
Molecular Functionindole-3-acetonitrile nitrilase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Arylacetonitrilase
  • EC number
  • Alternative names
    • NitAk2

Gene names

    • Name
      nit2
    • ORF names
      AKAW_01332

Organism names

Accessions

  • Primary accession
    G7X8S6
  • Secondary accessions
    • A0A0P1DJB4

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004511351-328Arylacetonitrilase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-278CN hydrolase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    328
  • Mass (Da)
    35,821
  • Last updated
    2012-01-25 v1
  • Checksum
    57E78101FBAE586C
MSSQVRVAVTQAEPVWLDLDATVKKTCDLIVEAAANGAQLVAFPECWIPGYPAWIWTRPVDMRLSSTYIQNSLKIDSPQMASIQKCAAENKIVVVLGFSENLHNSLYISQAIIGSDGKILTTRKKIKPTHMERTIFGDSFGDCLQSVVDTSAGRVGALSCWEHIQPLLKYHTYAQREQIHVAAWPPLFPHNEDGSLFSMSSEGTSSIARTYAIESQSFVLHTTTVIGQSGVDRMATHGGALMSTPGGGCSAIFGPDGRQLSQPIPSTEEGIIYADLDLDQIYHSKAFVDVCGHYSRPDLLWLGVEGSVKRHVRENAATVAAEAEQQEQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LN875496
EMBL· GenBank· DDBJ
CTQ87320.1
EMBL· GenBank· DDBJ
Genomic DNA
DF126449
EMBL· GenBank· DDBJ
GAA83217.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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