G7TKN8 · G7TKN8_XANOB

Function

function

Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site16-21NAD+ (UniProtKB | ChEBI)
Binding site19NADPH (UniProtKB | ChEBI)
Binding site20NADPH (UniProtKB | ChEBI)
Binding site40NADPH (UniProtKB | ChEBI)
Binding site57NADPH (UniProtKB | ChEBI)
Binding site114NADPH (UniProtKB | ChEBI)
Binding site114sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site114substrate
Binding site143sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site145sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site147NAD+ (UniProtKB | ChEBI)
Binding site147NADPH (UniProtKB | ChEBI)
Active site198Proton acceptor
Binding site198sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site251sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site261sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site262NAD+ (UniProtKB | ChEBI)
Binding site262NADPH (UniProtKB | ChEBI)
Binding site262sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site262-263substrate
Binding site263sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site286NADPH (UniProtKB | ChEBI)
Binding site288NADPH (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionglycerol-3-phosphate dehydrogenase (NADP+) activity
Molecular Functionglycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Molecular FunctionNAD binding
Biological Processcarbohydrate metabolic process
Biological Processglycerol-3-phosphate biosynthetic process
Biological Processglycerol-3-phosphate catabolic process
Biological Processglycerophospholipid metabolic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • EC number
  • Alternative names
    • NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase
    • NAD(P)H-dependent dihydroxyacetone-phosphate reductase

Gene names

    • Name
      gpsA
    • ORF names
      XOC_0318

Organism names

Accessions

  • Primary accession
    G7TKN8

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-167Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Domain187-325Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    345
  • Mass (Da)
    36,144
  • Last updated
    2012-01-25 v1
  • Checksum
    BEC3DC2C09DEAD53
MIAPMSDSTHKIAVLGAGSWGTALAALLARHGHPTVLWGRDAAMVDTIDRTHENARYLPGIALPDSLRATTDLQAAVADAAWILVVVPSHAFTETIRLIAPLRPAGAGVAWATKGFEPGSGRFLHEVARDILGPSVPLAVVTGPSFAKEVTLGLPTAITVHGDDATFAQAVADAMHGPTFRAYTGDDMVGAELGGAMKNVLAVATGVADGMQLGLNARAGLITRGLNEMLRLAAAIGARPETLMGLAGLGDLVLTCTGDLSRNRRLGLALGRGQSLNDAIRQIGQVVESVQMADEVMRQAEHHGIELPISNAVRAVLHGEITPEAGLKELLARERKPEYPQTLFT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003057
EMBL· GenBank· DDBJ
AEQ94555.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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