G7JJ97 · G7JJ97_MEDTR
- ProteinAminomethyltransferase
- Gene11437303
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids407 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
The glycine cleavage system catalyzes the degradation of glycine.
Catalytic activity
- N6-[(R)-S8-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N6-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 234 | substrate | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | glycine cleavage complex | |
Cellular Component | mitochondrion | |
Molecular Function | aminomethyltransferase activity | |
Molecular Function | methyltransferase activity | |
Molecular Function | transaminase activity | |
Biological Process | glycine catabolic process | |
Biological Process | methylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAminomethyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > Hologalegina > IRL clade > Trifolieae > Medicago
Accessions
- Primary accessionG7JJ97
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
The glycine cleavage system is composed of four proteins: P, T, L and H.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 40-295 | Aminomethyltransferase folate-binding | |||
Domain | 323-399 | Aminomethyltransferase C-terminal | |||
Sequence similarities
Belongs to the GcvT family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length407
- Mass (Da)44,105
- Last updated2014-10-01 v2
- MD5 ChecksumEAE1441923D2E52B928C04CBF2CD5FE3
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
G7JJ96 | G7JJ96_MEDTR | 11437303 | 433 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM001220 EMBL· GenBank· DDBJ | AES92654.2 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT135992 EMBL· GenBank· DDBJ | AFK35787.1 EMBL· GenBank· DDBJ | mRNA | ||
PSQE01000004 EMBL· GenBank· DDBJ | RHN64989.1 EMBL· GenBank· DDBJ | Genomic DNA |