G7JIK2 · SUNN_MEDTR
- ProteinLeucine-rich repeat receptor-like kinase protein SUNN
- GeneSUNN
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids974 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
LRR receptor kinase involved in the regulation of root growth and root nodule organogenesis (PubMed:16240175, PubMed:16941903, PubMed:22399647).
Involved in long distance nodulation signaling events (Probable) (PubMed:22399647).
Involved in the autoregulation of nodulation (AON), a long distance systemic signaling from root to shoot and back again, which allows legumes to limit the number of root nodules formed based on available nitrogen and previous rhizobial colonization (Probable) (PubMed:27135324).
Acts from shoot to root to control AON (PubMed:27135324, PubMed:28592666).
Interacts with CLE12 and CLE13 signaling to control nodule numbers (PubMed:22168914).
Required for the modulation of shoot-to-root auxin transport in response to altered nitrogen tissue concentrations and in the absence of rhizobia (PubMed:22399647).
Shoot-to-root auxin transport influences lateral root density and length (PubMed:22399647).
Involved in the regulation of root colonization by arbuscular mycorrhizal (AM) fungi (PubMed:16941903, PubMed:31477892).
Interacts with CLE33 and CL53 signaling to repress strigolactone biosynthetic genes and strigolactone content in the roots, and consequently reduces the promotion of further colonization by AM fungi (PubMed:31477892).
Involved in long distance nodulation signaling events (Probable) (PubMed:22399647).
Involved in the autoregulation of nodulation (AON), a long distance systemic signaling from root to shoot and back again, which allows legumes to limit the number of root nodules formed based on available nitrogen and previous rhizobial colonization (Probable) (PubMed:27135324).
Acts from shoot to root to control AON (PubMed:27135324, PubMed:28592666).
Interacts with CLE12 and CLE13 signaling to control nodule numbers (PubMed:22168914).
Required for the modulation of shoot-to-root auxin transport in response to altered nitrogen tissue concentrations and in the absence of rhizobia (PubMed:22399647).
Shoot-to-root auxin transport influences lateral root density and length (PubMed:22399647).
Involved in the regulation of root colonization by arbuscular mycorrhizal (AM) fungi (PubMed:16941903, PubMed:31477892).
Interacts with CLE33 and CL53 signaling to repress strigolactone biosynthetic genes and strigolactone content in the roots, and consequently reduces the promotion of further colonization by AM fungi (PubMed:31477892).
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]This reaction proceeds in the forward direction.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Molecular Function | receptor serine/threonine kinase binding | |
Biological Process | cell differentiation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLeucine-rich repeat receptor-like kinase protein SUNN
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > Hologalegina > IRL clade > Trifolieae > Medicago
Accessions
- Primary accessionG7JIK2
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 635-655 | Helical | ||||
Sequence: VVIAIVFATAVLMVIVTLHMM |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Dramatic increase in root nodule number when inoculated with Sinorhizobium meliloti (PubMed:16240175, PubMed:16941903, PubMed:22168914).
Inhibition of root growth in both the presence and absence of rhizobia (PubMed:16240175).
Increase in arbuscular mycorrhizal (AM) fungus colonization intensity in roots (hypermycorrhizal phenotype) when inoculated with AM fungi (PubMed:16941903).
Inhibition of root growth in both the presence and absence of rhizobia (PubMed:16240175).
Increase in arbuscular mycorrhizal (AM) fungus colonization intensity in roots (hypermycorrhizal phenotype) when inoculated with AM fungi (PubMed:16941903).
Features
Showing features for mutagenesis.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Mutagenesis | 575 | In sunn-2; dramatic increase in root nodule number when infected by Sinorhizobium meliloti, and inhibition of root growth in both the presence and absence of rhizobia. | ||||
Sequence: S → R | ||||||
Mutagenesis | 950 | In sunn-1; dramatic increase in root nodule number when infected by Sinorhizobium meliloti, and inhibition of root growth in both the presence and absence of rhizobia. | ||||
Sequence: R → K |
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-20 | |||||
Sequence: MKNITCYLLLLCMLFTTCYS | ||||||
Chain | PRO_0000448628 | 21-974 | Leucine-rich repeat receptor-like kinase protein SUNN | |||
Sequence: LNNDLDALLKLKKSMKGEKAKDDALKDWKFSTSASAHCSFSGVKCDEDQRVIALNVTQVPLFGHLSKEIGELNMLESLTITMDNLTGELPTELSKLTSLRILNISHNLFSGNFPGNITFGMKKLEALDAYDNNFEGPLPEEIVSLMKLKYLSFAGNFFSGTIPESYSEFQKLEILRLNYNSLTGKIPKSLSKLKMLKELQLGYENAYSGGIPPELGSIKSLRYLEISNANLTGEIPPSLGNLENLDSLFLQMNNLTGTIPPELSSMRSLMSLDLSINGLSGEIPETFSKLKNLTLINFFQNKLRGSIPAFIGDLPNLETLQVWENNFSFVLPQNLGSNGKFIYFDVTKNHLTGLIPPELCKSKKLKTFIVTDNFFRGPIPNGIGPCKSLEKIRVANNYLDGPVPPGIFQLPSVQIIELGNNRFNGQLPTEISGNSLGNLALSNNLFTGRIPASMKNLRSLQTLLLDANQFLGEIPAEVFALPVLTRINISGNNLTGGIPKTVTQCSSLTAVDFSRNMLTGEVPKGMKNLKVLSIFNVSHNSISGKIPDEIRFMTSLTTLDLSYNNFTGIVPTGGQFLVFNDRSFAGNPSLCFPHQTTCSSLLYRSRKSHAKEKAVVIAIVFATAVLMVIVTLHMMRKRKRHMAKAWKLTAFQKLEFRAEEVVECLKEENIIGKGGAGIVYRGSMANGTDVAIKRLVGQGSGRNDYGFKAEIETLGRIRHRNIMRLLGYVSNKDTNLLLYEYMPNGSLGEWLHGAKGCHLSWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLDADFEAHVADFGLAKFLYDPGASQSMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIIGRKPVGEFGDGVDIVGWINKTELELYQPSDKALVSAVVDPRLNGYPLTSVIYMFNIAMMCVKEMGPARPTMREVVHMLTNPPHSTSHNLINL | ||||||
Glycosylation | 75 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 104 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 123 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 136 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 250 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 274 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 312 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 346 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 508 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 513 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 556 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 585 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for repeat, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 92-116 | LRR 1 | ||||
Sequence: LNMLESLTITMDNLTGELPTELSKL | ||||||
Repeat | 117-141 | LRR 2 | ||||
Sequence: TSLRILNISHNLFSGNFPGNITFGM | ||||||
Repeat | 143-165 | LRR 3 | ||||
Sequence: KLEALDAYDNNFEGPLPEEIVSL | ||||||
Repeat | 166-188 | LRR 4 | ||||
Sequence: MKLKYLSFAGNFFSGTIPESYSE | ||||||
Repeat | 189-213 | LRR 5 | ||||
Sequence: FQKLEILRLNYNSLTGKIPKSLSKL | ||||||
Repeat | 238-262 | LRR 6 | ||||
Sequence: IKSLRYLEISNANLTGEIPPSLGNL | ||||||
Repeat | 263-286 | LRR 7 | ||||
Sequence: ENLDSLFLQMNNLTGTIPPELSSM | ||||||
Repeat | 288-309 | LRR 8 | ||||
Sequence: SLMSLDLSINGLSGEIPETFSK | ||||||
Repeat | 310-334 | LRR 9 | ||||
Sequence: LKNLTLINFFQNKLRGSIPAFIGDL | ||||||
Repeat | 335-358 | LRR 10 | ||||
Sequence: PNLETLQVWENNFSFVLPQNLGSN | ||||||
Repeat | 360-382 | LRR 11 | ||||
Sequence: KFIYFDVTKNHLTGLIPPELCKS | ||||||
Repeat | 383-406 | LRR 12 | ||||
Sequence: KKLKTFIVTDNFFRGPIPNGIGPC | ||||||
Repeat | 407-430 | LRR 13 | ||||
Sequence: KSLEKIRVANNYLDGPVPPGIFQL | ||||||
Repeat | 431-454 | LRR 14 | ||||
Sequence: PSVQIIELGNNRFNGQLPTEISGN | ||||||
Repeat | 456-477 | LRR 15 | ||||
Sequence: LGNLALSNNLFTGRIPASMKNL | ||||||
Repeat | 478-501 | LRR 16 | ||||
Sequence: RSLQTLLLDANQFLGEIPAEVFAL | ||||||
Repeat | 503-525 | LRR 17 | ||||
Sequence: VLTRINISGNNLTGGIPKTVTQC | ||||||
Repeat | 527-549 | LRR 18 | ||||
Sequence: SLTAVDFSRNMLTGEVPKGMKNL | ||||||
Repeat | 550-573 | LRR 19 | ||||
Sequence: KVLSIFNVSHNSISGKIPDEIRFM | ||||||
Repeat | 574-598 | LRR 20 | ||||
Sequence: TSLTTLDLSYNNFTGIVPTGGQFLV | ||||||
Domain | 685-972 | Protein kinase | ||||
Sequence: LKEENIIGKGGAGIVYRGSMANGTDVAIKRLVGQGSGRNDYGFKAEIETLGRIRHRNIMRLLGYVSNKDTNLLLYEYMPNGSLGEWLHGAKGCHLSWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLDADFEAHVADFGLAKFLYDPGASQSMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIIGRKPVGEFGDGVDIVGWINKTELELYQPSDKALVSAVVDPRLNGYPLTSVIYMFNIAMMCVKEMGPARPTMREVVHMLTNPPHSTSHNLI |
Sequence similarities
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length974
- Mass (Da)107,808
- Last updated2019-12-11 v2
- Checksum315BF83DFB7AE2A7
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY769943 EMBL· GenBank· DDBJ | AAW71475.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CM001220 EMBL· GenBank· DDBJ | AES89185.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation | |
PSQE01000004 EMBL· GenBank· DDBJ | RHN61330.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. |