G6XI51 · G6XI51_9PROT
- ProteinGlutamine--fructose-6-phosphate aminotransferase [isomerizing]
- GeneglmS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids608 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
Catalytic activity
- D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 2 | Nucleophile; for GATase activity | ||||
Sequence: C | ||||||
Active site | 603 | For Fru-6P isomerization activity | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | carbohydrate derivative binding | |
Molecular Function | glutamine-fructose-6-phosphate transaminase (isomerizing) activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | fructose 6-phosphate metabolic process | |
Biological Process | glutamine metabolic process | |
Biological Process | protein N-linked glycosylation | |
Biological Process | UDP-N-acetylglucosamine metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamine--fructose-6-phosphate aminotransferase [isomerizing]
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae > Gluconobacter
Accessions
- Primary accessionG6XI51
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for initiator methionine.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Initiator methionine | 1 | Removed | ||||
Sequence: M |
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-218 | Glutamine amidotransferase type-2 | ||||
Sequence: CGICGVVGHRPATPIIFEALRRLEYRGYDSAGIATLTVDGQIDRRRAAGKLDNLEAVLKEHPLSGVTGIGHTRWATHGAPTERNAHPHAAGQVAIVHNGIIENFGALKQELEAAGRVFVTETDSETVAHLVDFYLQQGKAPRDAAFAAIQRLEGAYAIAMIFQDHEGLLIGARHGAPLAVGYGDGEMFLGSDSLALAPLANRITYLEEGDWCELTPE | ||||||
Domain | 281-423 | SIS | ||||
Sequence: LPALPFDPATVPRMTVTACGSAYYAGMVGRYWLESLARLPIEIDVASELRYRNPPQPDKGVALLISQSGETADTLGVLRALKKAGQSVVSVLNVEHSTMGRESDLVLGMVAGPEISVASTKAFTAQLAVLAALSIEMARSRGT | ||||||
Domain | 456-598 | SIS | ||||
Sequence: MAQIVAEARDVLYLGRGICTPIAYEGALKLKEISYIHAEAYAAGELKHGPISLIDRTVPVVAIAPSTILFDKTLSNLQEAKARGGRILAFTDAAGAKRLEGVAERVVILPDVDAFVAPILYAIPVQILAYEVAILKGTDVDQP |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length608
- Mass (Da)65,181
- Last updated2012-01-25 v1
- Checksum40321201955ABAA7
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGQV01000002 EMBL· GenBank· DDBJ | EHH68491.1 EMBL· GenBank· DDBJ | Genomic DNA |