G6F0S5 · G6F0S5_9PROT
- ProteinPolyphosphate kinase
- Geneppk
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids725 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
Catalytic activity
- [phosphate](n) + ATP = [phosphate](n+1) + ADP
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 79 | ATP (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 407 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 437 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 467 | Phosphohistidine intermediate | ||||
Sequence: H | ||||||
Binding site | 500 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 596 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 624 | ATP (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | polyphosphate kinase complex | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | polyphosphate kinase activity | |
Biological Process | polyphosphate biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyphosphate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae
Accessions
- Primary accessionG6F0S5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Post-translational modification
An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 41-145 | Polyphosphate kinase N-terminal | ||||
Sequence: FINRELSWLDFNQRVVEEAKNTRNPLLERLRFLSISASNLDEFFSVRVAGLAGQVLEKLITTSPDGLTPAQQMAAIRERAKGLFEDQQQTYTELKQLLAETGIVV | ||||||
Domain | 157-336 | Polyphosphate kinase middle | ||||
Sequence: TWLKTYFMERIFPILTPIALDPAHPVPFIPNLNMALALRLISQKNDRNRKYVLILLPSQLPRFLVLPVSEKYPKTQRFVLLEDIITLFIAIIFPGYKIGNYGLLRVIRDTDVEFEEEAEDLVRSYETALKRRRRGVVIHLDIDSQLPTKLADLVIHALEVPAEDITVHNGLLGMVDVKQL | ||||||
Domain | 364-528 | Polyphosphate kinase C-terminal | ||||
Sequence: AFTALRSKDLLVYHPFESFDVVVRFLRQAAQDPQVLAIKQTLYRTSSNSPIVRALIEAAESGKSVTAIVELRARFDEEANIRLSRDLEAAGVQVVFGFADWKTHAKLSLVVRREGNMIRTYAHFGTGNYHPITAKIYTDLSYFTCNPKLTRDAAKLFNYVTGYAR | ||||||
Domain | 537-706 | Polyphosphate kinase C-terminal | ||||
Sequence: FSPLTIRKTLNELIEQEIEFVKDGKPGSIWLKINSLVDPRLIDRLYEASCAGVKINIVVRGICCLRPGVAGLSENIQVKSIVGRFLEHARVFAFGNGYELPSKHAKIYMSSADWMERNMDRRIEEMIPIIPDEIHNKVLNQLMVANLKDNLQSWHLDHDKKWRRVDVTEK |
Sequence similarities
Belongs to the polyphosphate kinase 1 (PPK1) family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length725
- Mass (Da)82,578
- Last updated2012-01-25 v1
- Checksum70B1A7A435F71B4E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGFR01000007 EMBL· GenBank· DDBJ | EHD13719.1 EMBL· GenBank· DDBJ | Genomic DNA |