G5EDV1 · G5EDV1_CAEEL
- ProteinFrizzled-4
- Genelin-17
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids558 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionG5EDV1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 207-228 | Helical | ||||
Sequence: WSIWFAAANAGVALFSFLTFAI | ||||||
Transmembrane | 240-260 | Helical | ||||
Sequence: VFYLSLCIFISSLPYLTPLFI | ||||||
Transmembrane | 295-316 | Helical | ||||
Sequence: YFFSTAAALWWLMFSFTLYLSG | ||||||
Transmembrane | 328-350 | Helical | ||||
Sequence: CSSYVHFVAWGLSSLATIIVLIF | ||||||
Transmembrane | 370-397 | Helical | ||||
Sequence: IALLWFVIVPRTICIVIGTCFIVGGFAS | ||||||
Transmembrane | 418-435 | Helical | ||||
Sequence: LMVKMGFFCALFILPNVI | ||||||
Transmembrane | 474-494 | Helical | ||||
Sequence: IYMTAVISSLATGFSCLMWVL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-17 | |||||
Sequence: MMHSLGIILLFIPLATG | ||||||
Chain | PRO_5015092011 | 18-558 | ||||
Sequence: SIFDQAVKGKCIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFPDPPELCMKPTEDEITGGFSAPRLPTKGSSSSSSKPTGCPSDLVDVDPHDPKSHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCHALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALFILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWKNFIFCGMCSSAPVKNPIEPSTRPLLEPPTAPPPQPPVYMQMATNPQNSWRPSKVV | ||||||
Disulfide bond | 28↔89 | |||||
Sequence: CIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMC | ||||||
Disulfide bond | 36↔82 | |||||
Sequence: CKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFIC | ||||||
Disulfide bond | 73↔111 | |||||
Sequence: CHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADC | ||||||
Disulfide bond | 104↔128 | |||||
Sequence: CEQVKADCFSILEEFGIGWPEPLNC |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 23-141 | FZ | ||||
Sequence: AVKGKCIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFPDPPELCMKP | ||||||
Region | 149-171 | Disordered | ||||
Sequence: GFSAPRLPTKGSSSSSSKPTGCP | ||||||
Compositional bias | 154-170 | Polar residues | ||||
Sequence: RLPTKGSSSSSSKPTGC | ||||||
Domain | 204-496 | G-protein coupled receptors family 2 profile 2 | ||||
Sequence: VRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCHALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALFILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSA | ||||||
Region | 522-558 | Disordered | ||||
Sequence: PSTRPLLEPPTAPPPQPPVYMQMATNPQNSWRPSKVV | ||||||
Compositional bias | 524-542 | Pro residues | ||||
Sequence: TRPLLEPPTAPPPQPPVYM | ||||||
Compositional bias | 543-558 | Polar residues | ||||
Sequence: QMATNPQNSWRPSKVV |
Sequence similarities
Belongs to the G-protein coupled receptor Fz/Smo family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Protein family/group databases
Sequence
- Sequence statusComplete
- Length558
- Mass (Da)62,226
- Last updated2011-12-14 v1
- Checksum73818EEE43EA6C30
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A078BS14 | A0A078BS14_CAEEL | lin-17 | 490 | ||
Q95Y45 | Q95Y45_CAEEL | lin-17 | 556 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 154-170 | Polar residues | ||||
Sequence: RLPTKGSSSSSSKPTGC | ||||||
Compositional bias | 524-542 | Pro residues | ||||
Sequence: TRPLLEPPTAPPPQPPVYM | ||||||
Compositional bias | 543-558 | Polar residues | ||||
Sequence: QMATNPQNSWRPSKVV |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U63557 EMBL· GenBank· DDBJ | AAC47301.1 EMBL· GenBank· DDBJ | mRNA | ||
BX284601 EMBL· GenBank· DDBJ | CCD70412.1 EMBL· GenBank· DDBJ | Genomic DNA |