G5ED33 · G5ED33_CAEEL
- ProteinEpidermal growth factor receptor pathway substrate 8 splice variant A
- Geneeps-8
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids917 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | apical part of cell | |
Cellular Component | brush border | |
Cellular Component | hemidesmosome | |
Cellular Component | plasma membrane | |
Molecular Function | actin binding | |
Molecular Function | actin filament binding | |
Molecular Function | cytoskeletal protein binding | |
Biological Process | actin filament bundle assembly | |
Biological Process | barbed-end actin filament capping | |
Biological Process | digestive tract morphogenesis | |
Biological Process | embryonic morphogenesis | |
Biological Process | epidermis morphogenesis | |
Biological Process | intermediate filament organization | |
Biological Process | maintenance of protein location | |
Biological Process | nematode larval development | |
Biological Process | regulation of Rho protein signal transduction | |
Biological Process | Rho protein signal transduction |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionG5ED33
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | G5ED33 | abl-1 P03949 | 6 | EBI-2315916, EBI-2315883 | |
BINARY | G5ED33 | R09H10.3 Q21882 | 3 | EBI-2315916, EBI-311857 | |
BINARY | G5ED33 | sorb-1 G5EC32 | 15 | EBI-2315916, EBI-325337 | |
BINARY | G5ED33 | wwp-1 Q9N2Z7 | 3 | EBI-2315916, EBI-317369 | |
BINARY | G5ED33 | ztf-17 P45972 | 3 | EBI-2315916, EBI-319208 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-94 | Disordered | ||||
Sequence: MRRGGSMGPPSGDPYQSRPSPGGYYYNRSTPGGQPAPSPSHSQQSASSHHPRGVPMSQPIARRSDYRTGSEQMTPRSDHRGPSMGYGNGGSVDQ | ||||||
Compositional bias | 31-52 | Polar residues | ||||
Sequence: PGGQPAPSPSHSQQSASSHHPR | ||||||
Compositional bias | 63-77 | Polar residues | ||||
Sequence: RSDYRTGSEQMTPRS | ||||||
Compositional bias | 307-321 | Basic and acidic residues | ||||
Sequence: HRYRTANRRDKKNQQ | ||||||
Region | 307-326 | Disordered | ||||
Sequence: HRYRTANRRDKKNQQPPDPN | ||||||
Coiled coil | 495-539 | |||||
Sequence: FDRLTLERERLEFEKAKIMERESRLRHEEKQIEDEKRRMHAEKDL | ||||||
Domain | 604-663 | SH3 | ||||
Sequence: KGGKLAVVTYDRGGQNTKELTVHKGEYLEVIFDERNWWECKNMHQRVGYVPHTILSMVPF | ||||||
Compositional bias | 668-691 | Polar residues | ||||
Sequence: YASPNHHNNSSSTGGYNNGHHQGP | ||||||
Region | 668-767 | Disordered | ||||
Sequence: YASPNHHNNSSSTGGYNNGHHQGPAQNVYRPPPPPLVSDAGVQVEIRREHVAPPPPPVVIPPPPPPVRTPTMEELLRMQQQQQQKQRKPPVEEPVYQPQP | ||||||
Compositional bias | 717-737 | Pro residues | ||||
Sequence: HVAPPPPPVVIPPPPPPVRTP | ||||||
Compositional bias | 741-755 | Polar residues | ||||
Sequence: ELLRMQQQQQQKQRK |
Sequence similarities
Belongs to the EPS8 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length917
- Mass (Da)104,365
- Last updated2011-12-14 v1
- Checksum4BC021037B43E170
Computationally mapped potential isoform sequences
There are 11 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4V6M3U0 | A0A4V6M3U0_CAEEL | eps-8 | 943 | ||
O18250 | O18250_CAEEL | eps-8 | 862 | ||
A0A061AKT4 | A0A061AKT4_CAEEL | eps-8 | 179 | ||
Q7YTG1 | Q7YTG1_CAEEL | eps-8 | 845 | ||
Q7YTG2 | Q7YTG2_CAEEL | eps-8 | 665 | ||
A0A061AJ42 | A0A061AJ42_CAEEL | eps-8 | 690 | ||
G5EFE0 | G5EFE0_CAEEL | eps-8 | 740 | ||
A0A061ADW6 | A0A061ADW6_CAEEL | eps-8 | 887 | ||
A0A061ACM2 | A0A061ACM2_CAEEL | eps-8 | 870 | ||
A0A061ACP8 | A0A061ACP8_CAEEL | eps-8 | 942 | ||
A0A4V0IJW4 | A0A4V0IJW4_CAEEL | eps-8 | 918 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 31-52 | Polar residues | ||||
Sequence: PGGQPAPSPSHSQQSASSHHPR | ||||||
Compositional bias | 63-77 | Polar residues | ||||
Sequence: RSDYRTGSEQMTPRS | ||||||
Compositional bias | 307-321 | Basic and acidic residues | ||||
Sequence: HRYRTANRRDKKNQQ | ||||||
Compositional bias | 668-691 | Polar residues | ||||
Sequence: YASPNHHNNSSSTGGYNNGHHQGP | ||||||
Compositional bias | 717-737 | Pro residues | ||||
Sequence: HVAPPPPPVVIPPPPPPVRTP | ||||||
Compositional bias | 741-755 | Polar residues | ||||
Sequence: ELLRMQQQQQQKQRK |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY611484 EMBL· GenBank· DDBJ | AAT37523.1 EMBL· GenBank· DDBJ | mRNA | ||
BX284604 EMBL· GenBank· DDBJ | CAJ44243.1 EMBL· GenBank· DDBJ | Genomic DNA |