G5E8D6 · G5E8D6_MOUSE
- ProteinEpidermal growth factor-containing fibulin-like extracellular matrix protein 2
- GeneEfemp2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids462 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | elastic fiber | |
Molecular Function | calcium ion binding | |
Molecular Function | heparin binding | |
Molecular Function | protein homodimerization activity | |
Biological Process | elastic fiber assembly | |
Biological Process | positive regulation of smooth muscle cell-matrix adhesion |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionG5E8D6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-46 | |||||
Sequence: MGGAVAETPDFCPPPPSLRMLPFASCLPGSLLLWAFLLLLLGAASP | ||||||
Chain | PRO_5015091905 | 47-462 | ||||
Sequence: QDPEEPDSYTECTDGYEWDADSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVISDLHGEGPPPPAAHAQQPNPCPQGYEPDEQESCVDVDECTQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCNQGYELHRDGFSCSDIDECGYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECETGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYVQVSDNRCLCPASNPLCREQPSSIVHRYMSITSERSVPADVFQIQATSVYPGAYNAFQIRSGNTQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 110-136 | Disordered | ||||
Sequence: LHGEGPPPPAAHAQQPNPCPQGYEPDE | ||||||
Domain | 142-182 | EGF-like | ||||
Sequence: DVDECTQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV | ||||||
Domain | 183-221 | EGF-like | ||||
Sequence: DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCV | ||||||
Domain | 262-301 | EGF-like | ||||
Sequence: DIDECGYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQ |
Sequence similarities
Belongs to the fibulin family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length462
- Mass (Da)51,350
- Last updated2011-12-14 v1
- Checksum4A85A5A9191AF8C0
Computationally mapped potential isoform sequences
There are 12 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9WVJ9 | FBLN4_MOUSE | Efemp2 | 443 | ||
E9PYW6 | E9PYW6_MOUSE | Efemp2 | 82 | ||
E9Q3N9 | E9Q3N9_MOUSE | Efemp2 | 402 | ||
E9Q3F3 | E9Q3F3_MOUSE | Efemp2 | 280 | ||
E9Q1U0 | E9Q1U0_MOUSE | Efemp2 | 128 | ||
E9Q2A0 | E9Q2A0_MOUSE | Efemp2 | 153 | ||
E9Q2T8 | E9Q2T8_MOUSE | Efemp2 | 191 | ||
F6R0V7 | F6R0V7_MOUSE | Efemp2 | 70 | ||
F7AYH6 | F7AYH6_MOUSE | Efemp2 | 120 | ||
F6Z1C2 | F6Z1C2_MOUSE | Efemp2 | 157 | ||
A0A494BAR1 | A0A494BAR1_MOUSE | Efemp2 | 404 | ||
A0A494BBF0 | A0A494BBF0_MOUSE | Efemp2 | 455 |
Keywords
- Technical term