G5E528 · G5E528_BOVIN

  • Protein
    Tudor domain-containing protein 5
  • Gene
    TDRD5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentP granule
Biological ProcessP granule organization
Biological ProcesspiRNA processing
Biological Processspermatogenesis

Names & Taxonomy

Protein names

  • Recommended name
    Tudor domain-containing protein 5

Gene names

    • Name
      TDRD5

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    G5E528

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain7-80HTH OST-type
Domain127-202HTH OST-type
Domain296-370HTH OST-type
Domain538-597Tudor
Region884-907Disordered
Region928-969Disordered

Sequence similarities

Belongs to the TDRD5 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,039
  • Mass (Da)
    116,732
  • Last updated
    2024-05-29 v3
  • Checksum
    7600B5A2AA611053
MSEQERIQECLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIANLVAKQKSNHKVRNSMQKGRASVCSGPSSRRRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFENAFANRFGRSFQYVQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEEKQRGWPAGKIFTQPFRMKQQGSYPIGFPVAKACFSQPTSNMEPPKQILGMERNSRSNVMETSRLNHSEKLNQLENTFKSVIAQIGPGGTINPELKHKIKFVVSRFPEGLLISKLLREFELIFKEQLSPKKLGFLNVIELVGALSDILHVEFREGEQDLLVFDADMKPLASDGAVSSVRNSFLVQPDKKTEAKACVSSPPRNSLSTAVIKETTWDCPSKNHKEPEQKIFKKPNLVVKPLQLQVEINKSQLSLAVANHDIPPDAVRDKKLCRLPPLDTSTLVGVFVEYILSPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYAMPECFIQPGHLCCVRISEDKWWYRVIIHRILGKQEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSRAVLQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENVPSKGFRDLNPLALYTKSSVTPEDIVLKELGYHSQQHYFNEDREISPQSKESDLYTLQDINDEKTFSHLGSVTSDEPLKDSKLNSLKIQDKSYEEDPKWSIPELKDLKEENEDEIPTGMPYLESVTIGDDIWDENWLPLQAKMGKESDAASHLFTSSLGGKKPYPSCKEIPQKDWCFSTPKDIWDDSWQPSGLVNGMKVEVQIPEGLGAQEKHIDTTRIQKQSNVKSASDSPALPKLEEFYISLIQSQQSAEGSQFEPSNIQTPPKQIQLSSTPTLVNSGSVEGSPESLENEDFSSSSAITVFKDTSQGAVDQLSLILSPEHQISQKFYIPRSTATAALGAAARLATSNSLLHWYPSVKKMET

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0AAA9TUL2A0AAA9TUL2_BOVINTDRD51180
A0A3Q1N5R0A0A3Q1N5R0_BOVINTDRD5972
A0AAA9TUB3A0AAA9TUB3_BOVINTDRD51161

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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