RGS7 and RGS11 are the key GTPase accelerating proteins in the mGluR6 pathway of retinal rod ON bipolar cells that set the sensitivity and time course of light-evoked responses.
RGS11 staining is present in dendritic tips of rod ON-retinal bipolar cell and cone ON-retinal bipolar cell. Genetic disruption of RGS11 produced delays in the ON-BPC-derived electroretinogram b-wave but no changes in the photoreceptor-derived a-wave.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.