G3W6S7 · G3W6S7_SARHA
- ProteinABR activator of RhoGEF and GTPase
- GeneABR
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids846 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | axon | |
Cellular Component | dendritic spine | |
Molecular Function | GTPase activator activity | |
Molecular Function | guanyl-nucleotide exchange factor activity | |
Biological Process | intracellular signal transduction |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Metatheria > Dasyuromorphia > Dasyuridae > Sarcophilus
Accessions
- Primary accessionG3W6S7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-70 | Disordered | ||||
Sequence: MELLLAGDFSYGADDYDGEGNEEQKVPPEGSETMPYIDESPTMSPQLSARSQGGGDGILPTPPEGLGPAV | ||||||
Compositional bias | 37-51 | Polar residues | ||||
Sequence: IDESPTMSPQLSARS | ||||||
Domain | 78-271 | DH | ||||
Sequence: MRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTLGHLFQKLASQLGVYKAFVDNYKIALETAEKCSQSNNQFQKISEELKVKAPKDSKDSHTSITMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINED | ||||||
Domain | 288-446 | PH | ||||
Sequence: QLVKDGFLVEMAESSRKLRHVFLFTDVLLCAKLKKTSVGKHQQYDCKWYIPLADLVFPSPEESEPSPQVHPFPDHELEDMKMKISALKSEIQKERANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQK | ||||||
Domain | 471-600 | C2 | ||||
Sequence: TVHNIPVTSNKDDDEAPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTTEPQWNEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVQTKNWHMDVI | ||||||
Domain | 634-832 | Rho-GAP | ||||
Sequence: VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEIGIYRISGVATDIQALKAVFDANNKDVLVMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRTLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKGHLTSASDIWSHDVMAQVQVLLYYLQHPPISF |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length846
- Mass (Da)96,177
- Last updated2021-04-07 v2
- Checksum717B41CB5921D06A
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A7N4NP34 | A0A7N4NP34_SARHA | ABR | 884 | ||
A0A7N4P1K3 | A0A7N4P1K3_SARHA | ABR | 853 | ||
A0A7N4NU98 | A0A7N4NU98_SARHA | ABR | 803 | ||
A0A7N4PCX4 | A0A7N4PCX4_SARHA | ABR | 859 | ||
G3W6S8 | G3W6S8_SARHA | ABR | 838 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 37-51 | Polar residues | ||||
Sequence: IDESPTMSPQLSARS |
Keywords
- Technical term