Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Iterative oxidation by TET1 is required for reprogramming of imprinting control regions and patterning of mouse sperm hypomethylated regions.Prasasya R.D., Caldwell B.A., Liu Z., Wu S., Leu N.A., Fowler J.M., Cincotta S.A., Laird D.J., Kohli R.M., Bartolomei M.S.View abstractSourceMGI: 1098693PubMedEurope PMCDev Cell 59:1010-1027.e8 (2024)Mapped to19
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 1098693PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1.Huang X., Balmer S., Lyu C., Xiang Y., Malik V., Wang H., Zhang Y., Cai B., Xie W.[...], Wang J.View abstractSourceMGI: 1098693PubMedEurope PMCDev Cell 59:465-481.e6 (2024)Mapped to41
Specific inhibition of TET1 in the spinal dorsal horn alleviates inflammatory pain in mice by regulating synaptic plasticity.Yang K., Wei R., Liu Q., Tao Y., Wu Z., Yang L., Wang Q.H., Wang H., Pan Z.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCNeuropharmacology 244:109799-109799 (2024)Mapped to11
Tet1 deficiency exacerbates oxidative stress in acute kidney injury by regulating superoxide dismutase.Fan Y., Yuan Y., Xiong M., Jin M., Zhang D., Yang D., Liu C., Petersen R.B., Huang K.[...], Zheng L.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCTheranostics 13:5348-5364 (2023)Mapped to11
Role of TET1-mediated epigenetic modulation in Alzheimer's disease.Armstrong M.J., Jin Y., Vattathil S.M., Huang Y., Schroeder J.P., Bennet D.A., Qin Z.S., Wingo T.S., Jin P.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCNeurobiol Dis 185:106257-106257 (2023)Mapped to15
DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation.Teghanemt A., Misel-Wuchter K., Heath J., Thurman A., Pulipati P., Dixit G., Geesala R., Meyerholz D.K., Maretzky T.[...], Issuree P.D.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCEMBO Rep 24:e55543-e55543 (2023)Mapped to32
TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype.Tricarico R., Madzo J., Scher G., Cohen M., Jelinek J., Maegawa S., Nagarathinam R., Scher C., Chang W.C.[...], Bellacosa A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1098693PubMedEurope PMCGastroenterology 164:921-936.e1 (2023)Mapped to30
DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation.Chen G.D., Fatima I., Xu Q., Rozhkova E., Fessing M.Y., Mardaryev A.N., Sharov A.A., Xu G.L., Botchkarev V.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1098693PubMedEurope PMCSci Adv 9:eabo7605-eabo7605 (2023)Mapped to61
Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.Liang X., Aranyi T., Zhou J., Guan Y., Hu H., Liu H., Susztak K.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCJ Am Soc Nephrol 34:572-589 (2023)Mapped to99+
The intrinsic and extrinsic effects of TET proteins during gastrulation.Cheng S., Mittnenzweig M., Mayshar Y., Lifshitz A., Dunjic M., Rais Y., Ben-Yair R., Gehrs S., Chomsky E.[...], Stelzer Y.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCCell 185:3169-3185.e20 (2022)Mapped to27
Loss of adipose TET proteins enhances beta-adrenergic responses and protects against obesity by epigenetic regulation of beta3-AR expression.Byun S., Lee C.H., Jeong H., Kim H., Kwon H.M., Park S., Myung K., An J., Ko M.View abstractSourceMGI: 1098693PubMedEurope PMCProc Natl Acad Sci U S A 119:e2205626119-e2205626119 (2022)Mapped to32
Single-Cell RNA-Seq Analysis Reveals Lung Epithelial Cell Type-Specific Responses to HDM and Regulation by Tet1.Zhu T., Brown A.P., Cai L.P., Quon G., Ji H.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCGenes (Basel) 13:880-880 (2022)Mapped to15
Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis.Hayashi T., Eto K., Kadoya Y.View abstractCategoriesFunction, ExpressionSourceMGI: 1098693PubMedEurope PMCDifferentiation 125:45-53 (2022)Mapped to37
TET1s deficiency exacerbates oscillatory shear flow-induced atherosclerosis.Qu K., Wang C., Huang L., Qin X., Zhang K., Zhong Y., Ma Q., Yan W., Li T.[...], Wang G.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1098693PubMedEurope PMCInt J Biol Sci 18:2163-2180 (2022)Mapped to24
CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.Teghanemt A., Pulipati P., Misel-Wuchter K., Day K., Yorek M.S., Yi R., Keen H.L., Au C., Maretzky T.[...], Issuree P.D.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCNat Commun 13:1477-1477 (2022)Mapped to29
Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.Ma L., Tang Q., Gao X., Lee J., Lei R., Suzuki M., Zheng D., Ito K., Frenette P.S., Dawlaty M.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1098693PubMedEurope PMCSci Adv 8:eabm3470-eabm3470 (2022)Mapped to22
The DNA dioxygenase Tet1 regulates H3K27 modification and embryonic stem cell biology independent of its catalytic activity.Chrysanthou S., Tang Q., Lee J., Taylor S.J., Zhao Y., Steidl U., Zheng D., Dawlaty M.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1098693PubMedEurope PMCNucleic Acids Res 50:3169-3189 (2022)Mapped to14
5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.Stoyanova E., Riad M., Rao A., Heintz N.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCElife 10:e66973-e66973 (2021)Mapped to22
Sex-specific chromatin remodelling safeguards transcription in germ cells.Huang T.C., Wang Y.F., Vazquez-Ferrer E., Theofel I., Requena C.E., Hanna C.W., Kelsey G., Hajkova P.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCNature 600:737-742 (2021)Mapped to63
Tet1 Regulates Astrocyte Development and Cognition of Mice Through Modulating GluA1.Xu W., Zhang X., Liang F., Cao Y., Li Z., Qu W., Zhang J., Bi Y., Sun C.[...], Li X.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1098693PubMedEurope PMCFront Cell Dev Biol 9:644375-644375 (2021)Mapped to11
The hepatic AMPK-TET1-SIRT1 axis regulates glucose homeostasis.Zhang C., Zhong T., Li Y., Li X., Yuan X., Liu L., Wu W., Wu J., Wu Y.[...], Zhong J.View abstractCategoriesFunctionSourceMGI: 1098693PubMedEurope PMCElife 10:e70672-e70672 (2021)Mapped to11